[Serotypes and antibody levels of group B streptococci in pregnant women].
[Serotypes and antibody levels of group B streptococci in pregnant women].
复制标题
孕妇B族链球菌血清型及抗体水平分析[J].
DOI：
10.11150/kansenshogakuzasshi1970.77.121
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
H. Nakashima
中科院分区：
文献类型：
--
作者：
S. Terakubo;Y. Ichiman;H. Takemura;Hiroyuki Yamamoto;J. Shimada;H. Nakashima
从1992年6月1日至2001年5月31日圣玛丽安娜大学医学院妇产科门诊1404例孕妇中分离出B群链球菌。采用溶血性链球菌分型免疫血清（Denka Seiken, Tokyo, Japan）对187例（13.3%）新鲜分离株GBS进行血清型检测。分别为VIII、VI、III、Ia、V、Ib和II型59株（31.6%）、46株（26.6%）、19株（10.2%）、16株（8.6%）、16株（6.4%）和3株（1.6%）。采用细菌凝集反应检测孕妇血清中GBS的滴度。阳性反应31例（57.4%），未见阳性反应23例（42.6%）。推测孕妇血清中抗体水平高在新生儿GBS感染的体内防御因子中起重要作用。
Group B streptococcus were isolated from 1404 pregnant out-patient women in the Department of Obstetrics and Gynecology, St. Marianna University School of Medicine, from June 1, 1992 to May 31, 2001. Serotype of 187 (13.3%) fresh isolates of GBS was determined by using hemolytic streptococcus-typing immune sera (Denka Seiken, Tokyo, Japan). With these strains there were 59 (31.6%), 46 (26.6%), 19 (10.2%), 16 (8.6%), 16 (8.6%), 12 (6.4%) and 3 (1.6%) indicating that their types were VIII, VI, III, Ia, V, Ib and II respectively. Also, bacterial agglutination reaction was employed for detection of titer to GBS in pregnant women serum. Positive reaction showed in 31 (57.4%) samples but 23 (42.6%) samples were not seen in this essay. It is assumed that the high antibody levels in pregnant women serum plays an important role as an in vivo defence factor in neonatal infection by GBS.