Associations between bipolar disorder and other psychiatric disorders during adolescence and early adulthood: A community-based longitudinal investigation

Associations between bipolar disorder and other psychiatric disorders during adolescence and early adulthood: A community-based longitudinal investigation
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DOI:
10.1176/appi.ajp.157.10.1679
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发表时间:
2000-10-01
影响因子:
17.7
通讯作者:
Brook, JS
Brook, JS
中科院分区:
医学1区
文献类型:
--
作者:
Johnson, JG;Cohen, P;Brook, JS

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目的:本研究调查了双相情感障碍和其他精神疾病在青少年和成年早期的横向和纵向联系。方法:1983年,对717名青少年及其母亲进行了精神病学访谈1985-1986年和1991- 1993年两次。结果:青少年期和成年早期的双相情感障碍共患精神疾病的范围很广。在考虑了青少年双相情感障碍后,青少年焦虑障碍与成年早期双相情感障碍风险增加唯一相关。躁狂症状在青春期与焦虑和抑郁障碍的风险增加在成年早期后,青少年焦虑和抑郁disorders accounted.Conclusions:青少年焦虑障碍可能会增加双相情感障碍或临床上显着的躁狂症状在成年早期的风险。有躁狂症状的青少年在成年早期患焦虑和抑郁症的风险可能会增加。
Objective: The study investigated cross-sectional and longitudinal associations between bipolar disorder and other psychiatric disorders during adolescence and early adulthood.Method: Psychiatric interviews were administered to a representative community sample of 717 youths and their mothers in 1983 (mean age of youths=14 years) and again in 1985-1986, and 1991-1993.Results: A wide range of psychiatric disorders co-occurred with bipolar disorder during adolescence and early adulthood. Adolescent anxiety disorders were uniquely associated with increased risk for early adulthood bipolar disorder after adolescent bipolar disorder was accounted for. Manic symptoms during adolescence were associated with increased risk for anxiety and depressive disorders during early adulthood after adolescent anxiety and depressive disorders were accounted for.Conclusions: Adolescents with anxiety disorders may be at increased risk for bipolar disorder or clinically significant manic symptoms during early adulthood. Adolescents with manic symptoms may be at increased risk for anxiety and depressive disorders during early adulthood.