Rhodium-catalyzed multiple C-H activation/highly meta-selective C-H amination between amidines and alkynes.
Rhodium-catalyzed multiple C-H activation/highly meta-selective C-H amination between amidines and alkynes.
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DOI：
10.1039/d0cc04885b
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发表时间：
2020-08
影响因子：
4.9
通讯作者：
Fen Xu;Yuan-Yuan Song-Yuan;Wen-Jing Zhu;Chun-sen Liu;Ya-Zhou Lu;M. Du
中科院分区：
文献类型：
--
作者：
Fen Xu;Yuan-Yuan Song-Yuan;Wen-Jing Zhu;Chun-sen Liu;Ya-Zhou Lu;M. Du
发展了一种脒和炔之间的多重C-H活化和分子间高间位选择性C-H胺化的串联过程。机理研究表明，该反应是通过两个不同的Rh（i）-Rh（iii）催化循环进行的，其中铑络合物I和罗达霉素中间体II是首次分离的。
A tandem process of multiple C-H activation and intermolecular highly meta-selective C-H amination between amidines and alkynes has been developed. Mechanistic studies demonstrate that the reaction is proposed to proceed through two different Rh(i)-Rh(iii) catalytic cycles, wherein Rhodium-complex I and Rhodacycle intermediate II were isolated for the first time.