MECHANICAL WORK OF BREATHING DERIVED FROM RIB CAGE AND ABDOMINAL V-P PARTITIONING
MECHANICAL WORK OF BREATHING DERIVED FROM RIB CAGE AND ABDOMINAL V-P PARTITIONING
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DOI：
10.1152/jappl.1976.41.5.752
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发表时间：
1976-01-01
影响因子：
3.3
通讯作者：
MEAD, J
中科院分区：
文献类型：
--
作者：
GOLDMAN, MD;GRIMBY, G;MEAD, J
从单独的胸腔和腹部容积位移的测量中得出的呼吸机械功的估计值（每个容积位移都与经胸压相关）包括呼吸期间可能发生的胸壁变形的弹性成本。通过增加经腹压的测量，将吸气功在膈肌和胸腔肌肉组织之间分配。将从单独的胸腔和腹部容积-压力（V-P）描记（由横膈膜、胸腔和腹部肌肉组织完成的功的总和）得出的呼吸机械功与从坎贝尔图（不包括任何畸变功）估计的呼吸功进行比较。在静息呼吸期间，2个估计值非常接近，与安静呼吸期间胸壁很少或没有变形一致。随着通气量的增加，从胸腔和腹部描记图得出的估计值系统性地显示出比从坎贝尔图得出的估计值更大的机械功，这与在较高通气水平时胸壁从放松的胸腹构型变形一致。在运动中达到换气时，坎贝尔图可能低估呼吸功达25%。
Estimates of the mechanical work of breathing [in humans] derived from measurements of separate rib cage and abdominal volume displacements, each plotted against transthoracic pressure, include the elastic cost of chest wall distortion which may occur during breathing. Inspiratory work was partitioned between the diaphragm and the rib cage musculature by adding measurements of transabdominal pressure. The mechanical work of breathing derived from separate rib cage and abdominal volume-pressure (V-P) tracings (the sum of work done by the diaphragm, rib cage and abdominal musculature) was compared with ventilatory work estimated from the Campbell diagram (which did not include any distortional work). During resting breathing, the 2 estimates were closely comparable, consistent with little or no distortion of the chest wall during quiet breathing. As ventilation increased the estimate developed from rib cage and abdominal tracings revealed systematically greater mechanical work than was estimated from the Campbell diagram, consistent with distortion of the chest wall from the relaxed thoracoabdominal configuration at higher levels of ventilation. At ventilations achieved during exercise, the Campbell diagram may underestimate the work of breathing by up to 25%.