Patent ductus arteriosus
Patent ductus arteriosus
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DOI：
10.1161/circulationaha.105.592063
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发表时间：
2006-10-24
期刊：
影响因子：
37.8
通讯作者：
Moore, John W.
中科院分区：
文献类型：
--
作者：
Schneider, Douglas J.;Moore, John W.
报告的PDA发病率因研究人群、考虑年龄和检测方法的方法学差异而不同。[16]虽然动脉导管通常在出生后48小时内功能性闭合，但一些权威人士认为，动脉导管未闭只有在3个月后才出现异常。17据报告，在足月出生的儿童中，动脉导管未闭的发病率为1/2000。18，19这占所有先天性心脏病的5%至10%。然而，如果我们包括患有“无声”未闭导管的儿童（通过超声心动图偶然发现的），其发病率估计高达1/500。20在大多数报告中，女性与男性的比例为2：1。
The reported incidence of PDA varies because of methodological differences related to the population group studied, age of consideration, and method of detection. 16 Although the ductus arteriosus usually is functionally closed within 48 hours of birth, some authorities consider the patent ductus to be abnormal only after 3 months of age. 17 In children who were born at term, the incidence of PDA has been reported to be 1 in 2000 births. 18, 19 This accounts for 5% to 10% of all congenital heart disease. However, if we include children with “silent” patent ductus (those discovered incidentally by echocardiography performed for another purpose), the incidence has been estimated to be as high as 1 in 500. 20 The female to male ratio is 2: 1 in most reports.