Twenty-four-hour light exposure and melatonin levels among shift workers
Twenty-four-hour light exposure and melatonin levels among shift workers
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DOI：
10.1097/01.jom.0000184855.87223.77
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发表时间：
2005-12-01
影响因子：
3.2
通讯作者：
Aronson, KJ
中科院分区：
文献类型：
--
作者：
Borugian, MJ;Gallagher, RP;Aronson, KJ
目的：我们试图测量卫生保健工作者在自然职业和居住环境中7天内的褪黑激素水平和24小时光强暴露。方法：5名上班族和17名白班或夜班轮转的护士，在7天的时间里，佩戴一个记录光照强度的装置，完成一份调查问卷，并提供3份唾液样本用于褪黑素检测。结果：与工作日相比，轮班工人的光照模式不规则，褪黑素水平异常。除了睡眠期间褪黑素水平低于正常水平外，轮班工人在起床和工作期间的褪黑素水平也高于正常水平。自我报告的轮班工作年数与测量的褪黑激素和光线有关。结论：轮班工作可以替代夜间光照和昼夜节律中断。
Objectives: We sought to measure melatonin levels and 24-hour light intensity exposure in health care workers over a 7-day period in natural occupational and residential settings. Methods: Five office workers and 17 nurses working either days or rotating night and day shifts wore a device to record light intensity exposure for one or two 7-day periods, completed a questionnaire, and provided three saliva samples for melatonin. Results: Rotating shift workers had irregular light exposure patterns and abnormal melatonin levels compared with those working days. In addition to lower-than-normal melatonin levels during sleep periods, rotating shift workers exhibited higher-than-normal melatonin levels on arising and during work. Self-reported years of shift work were correlated with measured melatonin and light. Conclusions: Rotating shift work is supported as a surrogate for exposure to light-at-night and circadian disruption.