Perspective taking deficits and their relationship with theory of mind abilities in patients with relapsing-remitting multiple sclerosis (RRMS)
Perspective taking deficits and their relationship with theory of mind abilities in patients with relapsing-remitting multiple sclerosis (RRMS)
复制标题
复发缓解型多发性硬化症 (RRMS) 患者的观点采择缺陷及其与心理理论能力的关系
DOI：
10.1080/23279095.2022.2114832
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Bruno D
中科院分区：
文献类型：
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作者：
Bruno D
近年来，有研究报道45%至70%的多发性硬化症（MS）患者存在认知缺陷，其中最突出的是与额叶相关的认知缺陷。在这些缺陷中，我们可以发现心理理论（ToM），这是一种推断他人感受和想法的能力。虽然有研究表明，认知能力依赖于更基本的技能，如透视能力（PT），但没有研究调查MS患者的这种关联。本研究的目的是调查MS患者的PT能力，并建立其与认知能力缺陷的关系。材料与方法对36例复发缓解型多发性硬化症（RRMS）患者和42例按年龄、性别和文化程度匹配的健康对照进行评价。两组都接受了预估发病前和当前的智力能力、PT、ToM（通过眼睛读心测试- rmet - and Faux Pas）和补充量表（疲劳、抑郁和残疾）的测试。结果：RRMS患者在PT和ToM测试中均与对照组有显著差异。PT测试与RMET呈正相关，RMET是我们的ToM测试之一。结论ToM与PT能力之间存在一定的关系。我们的研究结果对MS社会缺陷的评估和解释以及康复具有临床和学术意义。
Introduction and objectivesIn recent years, research has reported that between 45% and 70% of patients with Multiple Sclerosis (MS) have cognitive deficits, the most prominent being those associated with the frontal lobe. Among these deficits, we can find Theory of Mind (ToM), which is the ability to infer feelings and thoughts of others. Although it has been suggested that ToM relies on more basic skills, such as perspective taking (PT), no studies have investigated this association in patients with MS. The aim of this study was to investigate PT abilities in patients with MS and to establish their relationship with ToM deficits.Material and methods36 patients with relapsing-remitting multiple sclerosis (RRMS) and 42 healthy controls matched by age, sex and educational level were evaluated. Both groups were tested to estimate premorbid and current intellectual capacity, PT, ToM (Reading the Mind in the Eyes Test -RMET- and Faux Pas) and complementary scales (fatigue, depression and disability).Results: Patients with RRMS presented significant differences from controls in both PT and ToM tests. The PT test showed positive correlation with RMET, one of our ToM tests.ConclusionThe results show that there is a relationship between ToM and PT abilities. Our findings are of clinical and academic relevance to both the assessment and interpretation as well as the rehabilitation of social deficits in MS.