Adolescent survivors: A secondary analysis of a clinical trial targeting behavior change
Adolescent survivors: A secondary analysis of a clinical trial targeting behavior change
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DOI：
10.1002/pbc.20389
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发表时间：
2005-08-01
影响因子：
3.2
通讯作者：
Hudson, MM
中科院分区：
文献类型：
--
作者：
Cox, CL;McLaughlin, RA;Hudson, MM
背景放疗和化疗的晚期效应增加了儿童癌症幸存者患慢性健康问题的风险。幸存者的行为在改变这种风险方面很重要，但青少年和年轻的成年幸存者未能从事重要的健康促进行为，并经常进行高风险行为。这项二次分析重新评估了一种多成分的行为改变干预措施，这种干预措施以前对儿童癌症的青少年幸存者没有影响。Procedure.父母试验比较了干预组132名青少年幸存者和标准治疗组135名青少年幸存者在基线和1年时的疾病和治疗知识，对迟发效应风险的感知，以及健康风险和健康保护行为的频率（合并为单一总结性措施）。相比之下，二次分析分别检查了14种行为中的每一种。此外，还进行了协方差分析（ANCOVA），以检查健康行为的变化，同时对年龄、性别和基线行为的广泛变化进行统计控制。结果知识（P=0.038）、乳房自我检查（BSE）（P
Background. The late effects of radiation and chemotherapy increase childhood cancer survivors' risk of chronic health problems. Survivors' behavior is important in modifying this risk, yet adolescent and young adult survivors fail to engage in important health-promoting behaviors and frequently practice high-risk behaviors. This secondary analysis re-evaluated a multi-component behavior-change intervention that had previously demonstrated no impact in adolescent survivors of childhood cancer. Procedure. The parent trial compared 132 adolescent survivors in the intervention arm with 135 in the standard-care arm at baseline and at I year for disease and treatment knowledge, perception of late effects risk, and the frequency of health-risk and health-protective behaviors (combined as a single summative measure). In contrast, the secondary analysis examined each of the 14 behaviors separately. Additionally, an analysis of covariance (ANCOVA) was conducted to examine the change in health behaviors while statistically controlling for age, gender, and the wide variation in baseline behaviors. Results. Knowledge (P=0.038), breast self-examination (BSE) (P