Body proportionality of the small-for-date fetus: Is it related to aetiological factors?
Body proportionality of the small-for-date fetus: Is it related to aetiological factors?
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DOI：
10.1016/0378-3782(95)01717-8
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发表时间：
1996-07-05
影响因子：
2.5
通讯作者：
Pastorin, L
中科院分区：
文献类型：
--
作者：
Todros, T;Plazzotta, C;Pastorin, L
自超声引入产科诊断以来，将小于胎龄（SGA）胎儿分为对称和不对称的分类方法已被广泛应用。本研究的目的是评估SGA胎儿的身体比例与病因因素相关的可能性。超声测量头围（HC），腹围（AC）和股骨长度（FL）的348个SGA胎儿细分为病因组（结构和/或染色体异常，双胞胎，异常胎盘血管化，母亲营养不良，感染性疾病，药物成瘾，未知）。使用每对参数（HC-AC、HC-FL、FL-AC）之间的Z评分差异来评估不对称的存在及其程度。Z分数差异的分布为高斯分布; ± 1 S. D。和+2 S. D。作为定义不对称性的Z分数的截止值。在病因组之间，HC-AC不对称的频率没有显著差异。与原因不明的胎仔相比，胎盘血管化异常的SGA胎仔和先天性畸形胎仔的HC-FL差异更常见不对称，FL-AC差异不对称的频率更低。它的结论是，身体比例之间的SGA胎儿是一个连续体，它来自超声测量的信息是有限的，在临床实践中使用。
The classification of small-for-gestational-age (SGA) fetuses into symmetrical and asymmetrical has been widely used since the introduction of ultrasound into obstetric diagnosis. The purpose of this study was to assess the possibility of relating body proportionality of the SGA fetuses to aetiological factors. Ultrasound measurements of the head circumference (HC), abdominal circumference (AC) and femur length (FL) were obtained in 348 SGA fetuses subdivided into aetiological groups (structural and/or chromosomal anomalies, twins, abnormal placental vascularization, maternal malnutrition, infectious diseases, drug addiction, unknown). The difference in Z-score between each couple of parameters (HC-AC, HC-FL, FL-AC) was used to assess the presence of asymmetry and its degree. The distribution of the Z-score differences was Gaussian; + 1 S.D. and + 2 S.D. were chosen as cut-off values of the Z-score for the definition of asymmetry. No significant differences in the frequency of HC-AC asymmetry could be detected among aetiological groups. SGA fetuses with abnormal placental vascularization and those with congenital malformations were more frequently asymmetric for the difference HC-FL and less frequently asymmetric for the difference FL-AC compared to the ones of unknown cause. It is concluded that body proportionality among SGA fetuses is a continuum, and that information about it derived from ultrasound measurements is of limited use in clinical practice.