Somatostatin-like immunoreactive neurons in the hippocampus: An immunocytochemical study in the rat
Somatostatin-like immunoreactive neurons in the hippocampus: An immunocytochemical study in the rat
复制标题
海马中生长抑素样免疫反应性神经元：大鼠免疫细胞化学研究
DOI：
10.1016/0304-3940(82)90185-9
复制
发表时间：
1982
影响因子：
2.5
通讯作者：
V. Chan‐Palay
中科院分区：
文献类型：
--
作者：
C. Köhler;V. Chan‐Palay
本文用生长抑素抗体结合抗生物素蛋白-生物素免疫组织化学方法，研究了大鼠海马结构内生长抑素样（SOM-L）免疫反应细胞的层状分布和形态。SOM-L阳性细胞存在于整个海马的纵轴。这些神经元大多数为中等大小（15-20 μm）至大（25-30 μm），索马胞体呈多极或梭形。锥体细胞和颗粒细胞未见SOM-L阳性反应。SOM-L阳性细胞在阿蒙角的起始层和嵴髓层中有较好的分布，与齿状门区的多形细胞相吻合。这种地理上的分离可能意味着海马体功能的化学区室化。
Using antibodies to somatostatin in combination with the avidin-biotin immunohistochemical method, the laminar distribution and morphology of somatostatin-like (SOM-L) immunoreactive cells have been studied in the hippocampal formation of the rat. SOM-L positive cells are present throughout the longitudinal axis of the hippocampus. Most of these neurons are of medium (15–20 μm) to large (25–30 μm) size with soma of multipolar or fusiform shape. No pyramidal or granule cells contained SOM-L immunoreactivity. SOM-L-positive cells show a preferential distribution in the stratum oriens and stratum pyramidalae of Ammon's horn, and match the description of the polymorphic cells of the hilus area dentata. This geographic segregation may imply a chemical compartmentation of function in the hippocampus.