Taste receptors on the anterior tongue and nasoincisor ducts of rats contribute synergistically to behavioral responses to sucrose.
Taste receptors on the anterior tongue and nasoincisor ducts of rats contribute synergistically to behavioral responses to sucrose.
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DOI：
10.1037//0735-7044.107.4.694
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发表时间：
1993-08
影响因子：
1.9
通讯作者：
A. Spector;S. Travers;R. Norgren
中科院分区：
文献类型：
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作者：
A. Spector;S. Travers;R. Norgren
在四组大鼠中，通过允许它们在计算机控制的味觉计中舔溶液来测试对蔗糖的行为反应性（10-s试验; 0.01-1.0 M）。大鼠烧灼损伤的鼻切牙管（NID）的行为与对照组没有什么不同。双侧鼓索神经（CT）部分，从舌前部（AT）的味觉输入，大鼠表现出边缘衰减，他们对蔗糖的反应。然而，合并两种病变对浓度-反应曲线的影响最大。通过将曲线向右移动并降低渐近舔率，联合损伤使曲线下面积减少了三分之一。联合治疗的效果大于从任何一个单独的总和预测。这可能反映了NID和AT的初级传入轴突的中枢会聚。神经生理学数据已经证明了孤束核内的这种会聚。
In four groups of rats, behavioral responsiveness to sucrose was tested by allowing them to lick solutions in a computer-controlled gustometer (10-s trials; 0.01-1.0 M). Rats with cautery lesions of the nasoincisor ducts (NID) behaved no differently from controls. After bilateral chorda tympani nerve (CT) section, which removes taste input from the anterior tongue (AT), rats demonstrated a marginal attenuation in their responsiveness to sucrose. Combining the two lesions, however, had the greatest effect on the concentration-response curve. By shifting the curve to the right and lowering the asymptotic licking rate, the combined lesion reduced the area under the curve by one third. The effects of the combined treatments were larger than would be predicted from the sum of either one alone. This presumably reflects the central convergence of primary afferent axons from the NID and AT. Neurophysiological data have demonstrated such convergence within the nucleus of the solitary tract.