Pleural effusion in an immunocompetent woman caused by Mycobacterium fortuitum
Pleural effusion in an immunocompetent woman caused by Mycobacterium fortuitum
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DOI：
10.1099/jmm.0.024737-0
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发表时间：
2011-09-01
影响因子：
3
通讯作者：
Contini, Carlo
中科院分区：
文献类型：
--
作者：
Fabbian, Fabio;De Giorgi, Alfredo;Contini, Carlo
偶发分枝杆菌是一种非结核分枝杆菌，可导致肺炎、脓肿和脓胸等易患肺部疾病的患者。然而，胸膜炎伴胸腔积液是罕见的。在此，我们报告一位74岁无明显危险因素的免疫能力女性患者，以出血性胸腔积液为主要临床表现。通过计算机断层扫描发现胸膜结节，微生物分析显示偶发分支杆菌在没有其他病原体的情况下。患者接受了头孢曲松和环丙沙星治疗，4周后痊愈。据我们所知，这是第一例报道的出血性胸腔积液患者的免疫能力没有潜在的疾病。虽然非结核分支杆菌感染很少伴有胸膜受累，但在这种情况下应该考虑偶然分支杆菌，特别是当微生物学无法检测到常见病原体时，当临床情况不清楚时。
Mycobacterium fortuitum is a non-tuberculous mycobacterium that can cause pneumonia, abscess and empyema in subjects with predisposing lung diseases. However, pleurisy with effusion is rare. Herein, we report the case of a 74-year-old immunocompetent female patient without apparent risk factors, who suffered haemorrhagic pleural effusion as the main clinical manifestation. Pleural nodules were detected by computed tomography scan, and microbiological analysis revealed M. fortuitum in the absence of other pathogens. The patient was treated with ceftriaxone and ciprofloxacin, and full recovery ensued in 4 weeks. To our knowledge, this is the first reported case of haemorrhagic pleural effusion in an immunocompetent patient without underlying diseases. Although non-tuberculous mycobacterial infections are rarely accompanied by pleural involvement, M. fortuitum should be considered in such cases, especially when microbiology fails to detect the usual pathogens, and when the clinical picture is unclear.