Social communication disorder outside autism? A diagnostic classification approach to delineating pragmatic language impairment, high functioning autism and specific language impairment
Social communication disorder outside autism? A diagnostic classification approach to delineating pragmatic language impairment, high functioning autism and specific language impairment
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DOI：
10.1111/jcpp.12079
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发表时间：
2013-11-01
影响因子：
7.6
通讯作者：
Green, Jonathan
中科院分区：
文献类型：
--
作者：
Gibson, Jenny;Adams, Catherine;Green, Jonathan
语言和交流发育障碍由于症状重叠和病因不确定，给诊断带来了相当大的挑战。我们的目的是进一步阐明与自闭症诊断之外发生的社会沟通障碍相关的行为和语言概况。方法对6 ~ 11岁被诊断为语用性语言障碍（PLI）、高功能自闭症（HFA）和特殊语言障碍（SLI）的儿童进行同伴社交（PI）、限制性和重复性行为/兴趣（RRBIs）和语言能力的比较。使用多项逻辑回归的优势比（OR）来确定每个测量对诊断分组的重要性。方差分析用于调查PI测量的子量表得分的差异。结果较高的PI困难程度（OR=1.22, 95% CI=1.05-1.41）、RRBI （OR=1.23, 95% CI=1.06-1.42）和语言表达能力（OR=1.16, 95% CI=1.03-1.30）可以区分HFA和PLI。PLI与SLI的区别在于较高的PI困难（OR=0.82, 95% CI=0.70-0.96）和较高的语言表达能力（OR=0.88, 95% CI=0.77-0.98），但使用RRBI与SLI无法区分（OR=1.01, 95% CI=0.94-1.09）。两组在PI量表上均有显著差异(=1.38，F(4,56)=19.26, p
BackgroundDevelopmental disorders of language and communication present considerable diagnostic challenges due to overlapping of symptomatology and uncertain aetiology. We aimed to further elucidate the behavioural and linguistic profile associated with impairments of social communication occurring outside of an autism diagnosis.MethodsSix to eleven year olds diagnosed with pragmatic language impairment (PLI), high functioning autism (HFA) or specific language impairment (SLI) were compared on measures of social interaction with peers (PI), restricted and repetitive behaviours/interests (RRBIs) and language ability. Odds ratios (OR) from a multinomial logistic regression were used to determine the importance of each measure to diagnostic grouping. MANOVA was used to investigate differences in subscale scores for the PI measure.ResultsGreater degrees of PI difficulties (OR=1.22, 95% CI=1.05-1.41), RRBI (OR=1.23, 95% CI=1.06-1.42) and expressive language ability (OR=1.16, 95% CI=1.03-1.30) discriminated HFA from PLI. PLI was differentiated from SLI by elevated PI difficulties (OR=0.82, 95% CI=0.70-0.96) and higher expressive language ability (OR=0.88, 95% CI=0.77-0.98), but indistinguishable from SLI using RRBI (OR=1.01, 95% CI=0.94-1.09). A significant effect of group on PI subscales was observed (=1.38, F(4, 56)=19.26, p