Neighborhood characteristics associated with COVID-19 burden-the modifying effect of age.
Neighborhood characteristics associated with COVID-19 burden-the modifying effect of age.
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DOI：
10.1038/s41370-021-00329-1
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发表时间：
2021-05
影响因子：
4.5
通讯作者：
Stroustrup A
中科院分区：
文献类型：
--
作者：
Zhang X;Smith N;Spear E;Stroustrup A
社区特征与社区COVID-19发病率有关，但尚未研究年龄的调节作用。我们采用了全社区分析研究（NWAS）设计，系统地研究了不同年龄组中社区特征与COVID-19发病率之间的关系。伊利诺伊州公共卫生部公布了伊利诺伊州按邮政编码地区划分的每日COVID-19累计病例数。20岁以下、20 - 29岁、30-39岁、40-49岁、50-59岁、60-69岁、70-79岁和80岁以上8个年龄组报告了新冠肺炎病例数。我们回顾了从2020年5月23日到6月17日发布的这些数据，其中包含了所有八个年龄组的完整数据，并将这些数据与美国社区调查（ACS）测量的社区特征联系起来。按地理年龄划分的COVID-19累积发病率（每1000人的病例数）是通过将每日累积病例数除以每个邮政编码地区同一年龄组的人口来计算的。使用泊松回归模型检验个体特征与COVID-19发病率之间的关系。在邮政编码水平上，社区社会经济地位是儿童和工作年龄成年人中COVID-19发病率的重要危险因素，而不是老年人。社会人口和住房条件是老年人群新冠肺炎发病的重要危险因素。此外，我们还观察到多个年龄组中交通相关变量与COVID-19发病率之间存在显著关联。我们得出结论，年龄改变了社区特征与COVID-19发病率之间的关系。
Neighborhood characteristics have been linked to community incidence of COVID-19, but the modifying effect of age has not been examined. We adapted a neighborhood-wide analysis study (NWAS) design to systematically examine associations between neighborhood characteristics and COVID-19 incidence among different age groups. The number of daily cumulative cases of COVID-19 by zip code area in Illinois has been made publicly available by the Illinois Department of Public Health. The number of COVID-19 cases was reported for eight age groups (under 20, 20–29, 30–39, 40–49, 50–59, 60–69, 70–79, and 80+). We reviewed this data published from May 23 through June 17, 2020 with complete data for all eight age groups and linked the data to neighborhood characteristics measured by the American Community Survey (ACS). Geographic age-specific cumulative incidence (cases per 1000 people) of COVID-19 was calculated by dividing the number of daily cumulative cases by the population of the same age group at each zip code area. The association between individual characteristics and COVID-19 incidence was examined using Poisson regression models. At the zip code level, neighborhood socioeconomic status was a more important risk factor of COVID-19 incidence in children and working-age adults than in seniors. Social demographics and housing conditions were important risk factors of COVID-19 incidence in older age groups. We additionally observed significant associations between transportation-related variables and COVID-19 incidences in multiple age groups. We concluded that age modified the association between neighborhood characteristics and COVID-19 incidence.
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影响因子：
64.8
作者：
Li W;Moore MJ;Vasilieva N;Sui J;Wong SK;Berne MA;Somasundaran M;Sullivan JL;Luzuriaga K;Greenough TC;Choe H;Farzan M
通讯作者：
Farzan M
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FROME, EL;CHECKOWAY, H
通讯作者：
CHECKOWAY, H
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Lynch SM;Mitra N;Ross M;Newcomb C;Dailey K;Jackson T;Zeigler-Johnson CM;Riethman H;Branas CC;Rebbeck TR
通讯作者：
Rebbeck TR
影响因子：
5
作者：
Sy KTL;Martinez ME;Rader B;White LF
通讯作者：
White LF
影响因子：
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作者：
Pan, An;Liu, Li;Wu, Tangchun
通讯作者：
Wu, Tangchun