Brain activation during facial emotion processing
Brain activation during facial emotion processing
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DOI：
10.1006/nimg.2002.1097
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发表时间：
2002-07-01
期刊：
影响因子：
5.7
通讯作者：
Gur, RE
中科院分区：
文献类型：
--
作者：
Gur, RC;Schroeder, L;Gur, RE
功能性神经成像研究已经帮助识别了参与认知处理的神经系统，最近还表明了边缘对情绪刺激的激活。一些功能性磁共振成像（fMRI）研究报告了在暴露于情绪刺激时杏仁核反应增加，而其他研究则没有显示出这种激活。本研究旨在验证杏仁核的激活与刺激的情绪效价的相关性有关的假设。健康的年轻参与者（7名男性，7名女性）在高场（4特斯拉）扫描仪中进行研究，使用阻塞的“盒子车”设计中的血氧水平依赖（BOLD）信号变化。他们观看了来自不同种族和年龄的专业男女演员的面部表情，包括快乐、悲伤、愤怒、恐惧和厌恶，以及中性面孔。他们的任务在情绪歧视（表明情绪是积极的还是消极的）和年龄歧视（表明出题者年龄大于或小于30岁）之间交替进行。在这些方块中，情绪化和中性的面孔所占比例相同。边缘反应在情绪条件下比在年龄歧视条件下更大。这种反应在杏仁核中最为明显，但也存在于海马体和其他边缘区域的限定体素中。这些结果支持了杏仁核在情绪处理中的核心作用，并表明其对情绪表现的任务相关性的敏感性。(C) 2002 Elsevier Science （USA）。
Functional neuroimaging studies have helped identify neural systems involved in cognitive processing and more recently have indicated limbic activation to emotional stimuli. Some functional magnetic resonance imaging (fMRI) studies have reported increased amygdala response during exposure to emotional stimuli while others have not shown such activation. The present study was designed to test the hypothesis that activation of the amygdala is related to the relevance of the emotional valence of stimuli. Healthy young participants (7 men, 7 women) were studied in a high-field (4 tesla) scanner using blood oxygenation-level dependent (BOLD) signal changes in a blocked "box car" design. They viewed facial displays of happiness, sadness, anger, fear, and disgust as well as neutral faces obtained from professional actors and actresses of diverse ethnicity and age. Their task alternated between emotion discrimination (indicating whether the emotion was positive or negative) and age discrimination (indicating whether the poser was older or younger than 30). Blocks contained the same proportion of emotional and neutral faces. Limbic response was greater during the emotion than during the age discrimination conditions. The response was most pronounced in the amygdala, but was also present in the hippocampus and circumscribed voxels in other limbic regions. These results support the central role of the amygdala in emotion processing, and indicate its sensitivity to the task relevance of the emotional display. (C) 2002 Elsevier Science (USA).