Changes in the numbers of osteoclasts in newts under conditions of microgravity

Changes in the numbers of osteoclasts in newts under conditions of microgravity
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DOI:
10.1016/s0273-1177(98)00028-3
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发表时间:
1998-01-01
期刊:
LIFE SCIENCES: MICROGRAVITY RESEARCH
影响因子:
--
通讯作者:
Mitashov, VI
Mitashov, VI
中科院分区:
其他
文献类型:
--
作者:
Berezovska, OP;Rodionova, NV;Mitashov, VI

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骨吸收的强度和钙含量进行了研究,在完整的四肢骨蝾螈飞行的宇宙-2229号生物卫星上截肢后,他们的前肢和尾巴。X线微区分析显示术后第20天骨钙含量增加。组织学研究显示长骨骨内膜表面骨吸收激活。手术后暴露在生物卫星上的蝾螈的骨矿化水平与手术后的地面对照蝾螈相同,但多核破骨细胞数量的增加较低。(C)1998年空间研委会。爱思唯尔科技有限公司出版
Intensity of osteoclastic resorption and calcium content were investigated in intact limb bones of the newts flown on board of a biosatellite Cosmos-2229 after amputation of their forelimbs and tail. Using X-ray microanalysis it was shown an increase,in calcium content in the bones on 20(th) day after operation. Histological study revealed an activation of osteoclastic resorption on endosteal surface of long bones. The newts exposed after surgery-on a biosatellite had the same level of bone mineralisation as operated ground control ones, but the increase in number of polynuclear osteoclasts was lower. (C) 1998 COSPAR. Published by Elsevier Science Ltd.