Completion and timing of the three-dose human papillomavirus vaccine series among adolescents attending school-based health centers in Oregon
Completion and timing of the three-dose human papillomavirus vaccine series among adolescents attending school-based health centers in Oregon
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DOI：
10.1016/j.ypmed.2011.04.010
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发表时间：
2011-06-01
影响因子：
5.1
通讯作者：
Kurilo, Mary Beth
中科院分区：
文献类型：
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作者：
Gold, Rachel;Naleway, Allison L.;Kurilo, Mary Beth
Objective.许多青少年没有在推荐的时间范围内完成3剂人乳头瘤病毒疫苗系列，或者根本没有完成。考虑到给青少年，特别是弱势群体接种多剂量疫苗的挑战，我们评估了俄勒冈州19所学校卫生中心的人乳头瘤病毒疫苗系列的完成情况。在2007年在一个研究学校卫生中心启动人乳头瘤病毒疫苗系列的0-17岁人群中，我们确定了2007-2008年在学校卫生中心或在俄勒冈州免疫信息系统中发现的所有后续人乳头瘤病毒剂量。我们描述了完成疫苗系列的比例和剂量之间的平均间隔，按年龄，种族和保险状态分层。2007年，450人启动了人类乳头瘤病毒系列。到2008年12月，其中51%的人接受了所有3剂疫苗。系列完成随着年龄的增长显着增加，种族组之间的差异显着（最高的白色人（56%）;最低的黑人（38%）），并没有显着不同的保险状态。剂量之间的平均间隔没有显着差异的种族或保险状态。即使在具有挑战性的条件下，以学校为基础的保健中心也为脆弱的青年提供出色的预防保健。这些结果支持了维持和扩大以学校为基础的健康中心在弱势青少年人群中的重要性。(C)2011 Elsevier Inc. All rights reserved.
Objective. Many adolescents do not complete the 3-dose human papillomavirus vaccine series in the recommended time frame, or at all. Given the challenges of administering a multi-dose vaccine to adolescents, especially those in vulnerable populations, we evaluated completion of the human papillomavirus vaccine series in 19 of Oregon's school-based health centers.Methods. Among persons aged 0-17 who initiated the human papillomavirus vaccine series at a study school-based health center in 2007, we identified all subsequent human papillomavirus doses administered at the school-based health centers, or found in Oregon's immunization information system, in 2007-2008. We describe the proportion completing the vaccine series and mean intervals between doses, stratified by age, race, and insurance status.Results. Four hundred fifty persons initiated the human papillomavirus series in 2007. By December 2008, 51% of these had received all 3 doses. Series completion increased significantly with age, differed significantly between race groups (highest among white persons (56%); lowest among black persons (38%)), and did not differ significantly by insurance status. Mean intervals between doses did not differ significantly by race or insurance status.Conclusions. Even in challenging conditions, school-based health centers provide excellent preventive care to vulnerable youth. These results support the importance of maintaining and expanding school-based health center access in vulnerable adolescent populations. (C) 2011 Elsevier Inc. All rights reserved.