Are There Gender-Specific Risk Factors for Suicidal Activity among Patients with Schizophrenia and Depression?
Are There Gender-Specific Risk Factors for Suicidal Activity among Patients with Schizophrenia and Depression?
复制标题
DOI：
10.1111/j.1943-278x.2012.00116.x
复制
发表时间：
2012-12-01
影响因子：
3.2
通讯作者：
Faull, Robert N.
中科院分区：
文献类型：
--
作者：
Kaplan, Kalman J.;Harrow, Martin;Faull, Robert N.
精神分裂症和抑郁症患者的自杀行为是否存在性别特异性风险因素？对来自芝加哥随访研究的74名精神分裂症患者（51名男性，23名女性）和77名单相非精神病性抑郁症患者（26名男性，51名女性）在住院后2年和7.5年再次进行前瞻性研究。在我们的精神分裂症和抑郁症样本中，只有男性的早期产后整体功能不佳与后来的自杀行为显著相关。在男性精神分裂症患者中，精神病症状的早期表现与后来的自杀活动有关。早期认知功能障碍与四组患者中的任何一组患者后来的自杀活动均无显著相关性。研究结果必须被视为探索性的，并有望推动未来对这一重要课题的研究。
Are there gender-specific risk factors for suicidal activity among patients with schizophrenia and depression? A total of 74 schizophrenia patients (51 men, 23 women) and 77 unipolar nonpsychotic depressed patients (26 men, 51 women) from the Chicago Follow-up Study were studied prospectively at 2 years posthospitalization and again at 7.5 years. Poor early posthospital global functioning is significantly associated with later suicidal activity only for men in both our schizophrenia and depressive samples. Early display of psychotic symptoms is associated with later suicidal activity among male schizophrenia patients. Early cognitive impairment is not significantly associated with later suicidal activity for any of the four groups of patients. The study results must be seen as exploratory and will hopefully spur future research on this important topic.