PRIMARY CUTANEOUS ASPERGILLOSIS IN A LEUKEMIC CHILD
PRIMARY CUTANEOUS ASPERGILLOSIS IN A LEUKEMIC CHILD
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DOI：
10.1001/archderm.114.1.78
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发表时间：
1978-01-01
影响因子：
--
通讯作者：
VATS, TS
中科院分区：
文献类型：
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作者：
CARLILE, JR;MILLET, RE;VATS, TS
原发性皮肤曲霉病是罕见的。原发性皮肤感染由黄曲霉在儿童白血病描述。病变的特征是伴有疼痛和瘙痒的红斑斑疹和丘疹，随后迅速发展为溃疡和中央黑色痂，并伴有隆起的红斑边界。观察到局部制霉菌素治疗的良好反应。在病人身上看到的多发皮肤病变很可能是由于在静脉输注部位附近的初次接种，随后局部淋巴扩散。
Primary cutaneous aspergillosis is rare. A primary skin infection by Aspergillus flavus in a child with leukemia is described. The lesions were characterized by erythematous macules and papules associated with pain and itching, followed by a rapid progression to ulcers and central black eschars with a raised erythematous border. A favorable response to topical nystatin therapy was observed. The multiple cutaneous lesions seen in the patient were most likely due to primary inoculation near the site of i.v. infusion with subsequent local lymphatic spread.