The length and complexity of mesentery are related to the locoregional recurrence of the carcinoma in gut
The length and complexity of mesentery are related to the locoregional recurrence of the carcinoma in gut
复制标题
肠系膜的长度和复杂性与肠道癌的局部复发有关
DOI：
10.1016/j.mehy.2017.04.013
复制
发表时间：
2017-06-01
影响因子：
4.7
通讯作者：
Gong, Jianping
中科院分区：
文献类型：
--
作者：
Shen, Jie;Xie, Daxing;Gong, Jianping
局部区域复发是肠道癌的主要复发方式，预后差。随着全直肠系膜及全结肠系膜切除术(TME/CME)的发展，结直肠癌局部复发率明显降低。人们将其归因于淋巴清扫术的改进，但淋巴转移难以解释无患者局部复发的原因。此前，我们已证实“转移V”在中胃和直肠系膜中的存在，并推测它是局部复发的主要危险因素之一。因此，我们认为完整的肠系膜切除可以有效地减少转移V，防止癌漏，改善患者的预后。由于肠系膜的长度和复杂性不同，肠系膜切除的难度也不同。同时，不同消化道，甚至同一器官不同部位的局部复发率也有明显差异。因此，我们推测肠系膜的长度和复杂性可能是肠腺癌局部区域复发的一个危险因素。(C)2017爱思唯尔有限公司。保留所有权利。
Local-regional relapse is the main recurrence pattern of the carcinoma in gut, and leads to poor prognosis. With the development of the total mesorectal and complete mesocolic excision (TME/CME), the local relapse rate of colorectal cancer has significantly decreased. People attributed it to the improvement of lymphadenectomy, but lymphatic metastasis is difficult to explain the local relapse in NO patients. Previously, we have proven the existence of "Metastasis V" in mesogastrium and mesocolorectum, and supposed that it is one of the major risk factors in local recurrence. Therefore, we think complete mesentery excision can effectively reduce "Metastasis V", prevent cancer leak and improve patients' outcome. Due to the different length and complexity of mesentery, the difficulty of mesentery excision varies. Meanwhile, there is an obvious distinction of local relapse rate in different alimentary tract, even in different segment of a same organ. Thus we assume that the length and complexity of mesentery may be a risk factor of the locoregional recurrence of the carcinoma in gut. (C) 2017 Elsevier Ltd. All rights reserved.