The Healthy Eating Plate Advice for Migraine Prevention: An Interventional Study
The Healthy Eating Plate Advice for Migraine Prevention: An Interventional Study
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DOI：
10.3390/nu12061579
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发表时间：
2020-06-01
期刊：
影响因子：
5.9
通讯作者：
Vernieri, Fabrizio
中科院分区：
文献类型：
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作者：
Altamura, Claudia;Cecchi, Gianluca;Vernieri, Fabrizio
我们的目的是评估健康饮食餐盘（HEP）教育对偏头痛频率和残疾的影响。在三个评估时间（T-12 =筛查，干预前12周；T0 =教育HEP干预时间；T12 = 12周随访），入组受试者接受人体测量和饮食模式，每月偏头痛天数（MMDs）和残疾量表（偏头痛残疾评估评分（MIDAS）， MIDAS A, MIDAS B）的评估。HEP评分评估了饮食建议的依从性。我们招募了240名偏头痛患者中的204名，其中97名患者完成了随访。我们将HEP评分从T0增加到T12的患者定义为拥护者，将MMDs减少至少30%的患者定义为应答者。从T0到T12，患者MMDs显著降低。特别是，与无反应者相比，反应者减少了红肉、加工肉类和碳水化合物的摄入量。减少碳水化合物的消耗也与感知残疾（MIDAS）和头痛强度（MIDAS B）的降低有关。Logistic回归证实HEP评分的增加和总碳水化合物的减少与MMDs的减少有关。这项研究表明，坚持HEP的建议，特别是减少碳水化合物、红肉和加工肉类的消费，对偏头痛的管理，减少偏头痛的频率和残疾是有用的。试验注册：ISRCTN14092914。
We aimed at evaluating the effect of the Healthy Eating Plate (HEP) education on migraine frequency and disability. At three evaluation times (T-12 = screening, 12 weeks before the intervention; T0 = time of the educational HEP intervention; and T12 = 12-week follow-up), the enrolled subjects underwent assessment of anthropometric and dietary patterns, monthly migraine days (MMDs), and disability scales (Migraine Disability Assessment score (MIDAS), MIDAS A, MIDAS B). The HEP score estimated adherence to dietary advice. We enrolled 204 out of 240 screened migraineurs, of these, 97 patients completed the follow-up. We defined ADHERENTS as patients presenting an increase in HEP scores from T0 to T12 and RESPONDERS as those with a reduction of at least 30% in MMDs. ADHERENTS presented a significant decrease in MMDs from T0 to T12. In particular, RESPONDERS reduced red, processed meat and carb intake compared to NON-RESPONDERS. Reduction in carb consumption also related to a decrease in perceived disability (MIDAS) and headache pain intensity (MIDAS B). Logistic regression confirmed that the HEP score increase and total carb decrease were related to a reduction in MMDs. This study showed that adherence to the HEP advice, particularly the reduction in carb, red and processed meat consumption, is useful in migraine management, reducing migraine frequency and disability. Trial registration: ISRCTN14092914.