Catalytic Asymmetric Synthesis
Catalytic Asymmetric Synthesis
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DOI：
10.5059/yukigoseikyokaishi.50.1131
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发表时间：
1992-12
影响因子：
0.2
通讯作者：
R. Noyori
中科院分区：
文献类型：
--
作者：
R. Noyori
使用手性金属络合物的均相催化为手性的化学倍增提供了一般原理。通过适当的过渡金属或主族元素与适当设计的手性有机元素的组合，可以催化合成多种光学活性物质。这种化学不仅适用于在实验室中立体选择性地制备手性化合物，甚至在工业水平上也是有用的。这一领域的最新进展极大地提高了有机合成的潜力。并对其现状进行了讨论。
Homogeneous catalysis using chiral metal complexes provides a general principle for chemical multiplication of chirality. A wide range of optically active substances can be synthesized catalytically by the appropriate combination of transition metals or main group elements and suitably designed chiral organic elements. This chemistry is useful not only for stereoselective preparation of chiral compounds in laboratories but also even on industrial level. The recent progress in this field greatly raised the potential of organic synthesis in general. The current status is discussed.