ENDOCRINE, CARDIOVASCULAR, AND PSYCHOLOGICAL CORRELATES OF OLFACTORY SENSITIVITY CHANGES DURING THE HUMAN MENSTRUAL-CYCLE
ENDOCRINE, CARDIOVASCULAR, AND PSYCHOLOGICAL CORRELATES OF OLFACTORY SENSITIVITY CHANGES DURING THE HUMAN MENSTRUAL-CYCLE
复制标题
DOI：
10.1037/h0077755
复制
发表时间：
1981-01-01
期刊：
影响因子：
--
通讯作者：
LOWRY, LD
中科院分区：
文献类型：
--
作者：
DOTY, RL;SNYDER, PJ;LOWRY, LD
嗅觉敏感度(d‘’)的信号检测测量以及血压、心率、体温、鼻气流和呼吸频率的测量在.simeq内反复建立。未服用口服避孕药的17个月经周期、口服避孕药的6个月经周期和3名男性的6个等值周期每隔一天进行一次2.5h的测试。此外，采用放射免疫法测定血清黄体生成素[促黄体生成素、黄体生成素]、卵泡刺激素[卵泡刺激素]、雌酮、雌二醇、孕酮和睾酮水平，以及对MoOS月经窘迫问卷(MDQ)的反应。在服用和不服用口服避孕药的妇女中，嗅觉敏感度的峰值出现在月经后半月、月经中期和黄体中期。在服用口服避孕药的人群中，d‘’的波动与循环激素水平之间缺乏相关性，这表明除了性腺激素外，其他因素也是导致这些变化的原因。正常骑行的女性的所有激素以及体温、鼻部气流、MDQ水分保持和疼痛程度量表在整个周期阶段也都有显著波动。在口服避孕药组中，在整个周期中观察到的体温以及循环中的促黄体生成素和雌酮水平的变化很小，但在统计学上有显著意义。在所有三组受试者中，都注意到了在测试期内和跨测试期的一些变量之间的相互关系。研究结果与月经周期中一些感觉系统的波动有关。
Signal detection measures of olfactory sensitivity (d'') and measures of blood pressure, heart rate, body temperature, nasal airflow, and respiration rate were repeatedly established within .simeq. 2.5 h test sessions held every other day across 17 menstrual cycles of women not taking oral contraceptives, 6 menstrual cycles of women taking oral contraceptives and 6 equivalent time periods of 3 men. In addition, radioimmunoassay-determined serum levels of luteinizing hormone [lutropin, LH], follicle stimulating hormone [follitropin], estrone, estradiol, progesterone and testosterone, as well as responses to the Moos Menstrual Distress Questionnaire (MDQ), were established daily or bidaily throughout the study periods. Peaks in olfactory sensitivity were noted during the 2nd half of menses, midcycle and midluteally in women taking and in women not taking oral contraceptives. The lack of correlation between the fluctuations in d'' and the circulating hormone levels in the group using oral contraceptives suggests factors other than gonadal hormones were responsible for these changes. Significant fluctuations were also noted across the cycle phases of the normally cycling women for all the hormones examined, as well as for body temperature, nasal airflow, and the MDQ Water Retention and Pain Scales. In the oral contraceptive group, very small but statistically significant changes were observed across the cycle in body temperature and in circulating levels of LH and estrone. Interrelations between a number of the variables were noted both within and across the test periods in all 3 subject groups. The results are discussed in relation to fluctuations reported in a number of sensory systems during the menstrual cycle.