Somatosensory evoked potential in neurosyphilis
Somatosensory evoked potential in neurosyphilis
复制标题
神经梅毒的体感诱发电位
DOI：
10.1007/s00415-002-0813-2
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发表时间：
2002
影响因子：
6
通讯作者：
K. Motoyoshi
中科院分区：
文献类型：
--
作者：
H. Mochizuki;K. Kamakura;M. Kanzaki;T. Nishii;H. Matsuo;K. Motoyoshi
自从开发出有效的抗生素疗法以来，神经梅毒的发生已经变得越来越少。作为获得性免疫缺陷综合征的并发症，梅毒患者的数量逐渐增加，但神经梅毒的诊断有时很困难。我们描述了六名神经梅毒患者，并对他们的胫神经体感诱发电位进行了分析。其中 4 例（包括 2 例没有脊髓痨症状）出现 P15-N21 延迟或 N21 缺失。这些异常现象通过梅毒治疗得到改善。胫神经 SEP 的分析为神经梅毒的诊断和神经梅毒进展程度的评估提供了有用的工具。
Since the development of effective antibiotic therapy, the occurrence of neurosyphilis has become less frequent. The number of syphilitic patients is gradually increasing as a complication in acquired immunodeficiency syndrome, but the diagnosis of neurosyphilis sometimes is difficult. We describe six patients with neurosyphilis and an analysis of their tibial nerve somatosensory evoked potentials. Four of them, including two with no tabes dorsalis symptoms, had delayed P15-N21 or the absence of N21. These abnormalities were ameliorated by treatment for syphilis. Analysis of tibial nerve SEPs provides a useful tool for the diagnosis of neurosyphilis and the evaluation of the extent to which neurosyphilis has progressed.