NEW ELEMENTS FOR AN UPDATED CLASSIFICATION OF THE CARCINOMAS OF THE STOMACH
NEW ELEMENTS FOR AN UPDATED CLASSIFICATION OF THE CARCINOMAS OF THE STOMACH
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DOI：
10.1016/s0344-0338(11)80878-2
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发表时间：
1995-07-01
影响因子：
2.8
通讯作者：
SOBRINHOSIMOES, M
中科院分区：
文献类型：
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作者：
CARNEIRO, F;SEIXAS, M;SOBRINHOSIMOES, M
根据对213例有治愈潜力的胃癌患者的研究结果，我们提出以下胃癌的组织学分类：分离细胞癌（6.6%），腺癌（41.8%），实体癌（13.1%）和混合性癌（38.5%）。一半的混合性癌表现为主要的分离细胞模式，而另一半的分离细胞是次要成分（主要成分是腺细胞、实体细胞或两者兼而有之）。混合癌患者的生存率明显低于其他组织学类型的胃癌患者，无论肿瘤的位置和是否包含在术后死亡序列中。该分类在多因素分析中保持了其独立的预后意义，在胃癌患者中，它是继TNM分期和静脉浸润前的第二大预后因素。
Based upon the results of a thorough study of 213 patients submitted to potentially curative resection we propose the following histologic classification of gastric carcinoma: isolated-cell carcinoma (6.6%), glandular carcinoma (41.8%), solid carcinoma (13.1%) and mixed carcinoma (38.5%). Half of the mixed carcinomas displayed a predominant isolated-cell pattern, whereas in the other half the isolated-cells were a minor component (the predominant component being either glandular, solid, or both).The survival of patients with mixed carcinomas is significantly worse than those of patients with other histologic types of gastric carcinoma regardless of the site of tumors and the inclusion, or not, in the series, of post-operative deaths.The proposed classification keeps its independent prognostic significance in a multifactorial analysis, appearing as the second most important prognostic factor in patients with gastric carcinomas, after the TNM staging and before venous invasion.