Viable use of 2-substituted thiazolidine-4-methanol diastereoisomeric mixtures during asymmetric borane reduction of aromatic ketones
Viable use of 2-substituted thiazolidine-4-methanol diastereoisomeric mixtures during asymmetric borane reduction of aromatic ketones
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DOI：
10.1016/s0957-4166(97)00480-1
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发表时间：
1997-11-13
影响因子：
--
通讯作者：
Paolini, F
中科院分区：
文献类型：
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作者：
Calmes, M;Escale, F;Paolini, F
研究了在不可分离的2-取代噻唑烷-4-甲醇非对映异构体混合物存在下，硼烷还原芳香酮的反应。随着噻唑烷空间位阻的增加，得到了中等到高度的对映体过量。(C)1997年爱思唯尔科学有限公司。
The reduction of aromatic ketones by borane in the presence of the inseparable diastereoisomeric mixture of 2-substituted thiazolidine-4-methanol has been investigated. Modest to high enantiomeric excesses were obtained increasing with thiazolidine steric hindrance. (C) 1997 Elsevier Science Ltd.