Three-dimensional echocardiographic measurement of left ventricular mass: Comparison with magnetic resonance imaging and two-dimensional echocardiographic determinations in man
Three-dimensional echocardiographic measurement of left ventricular mass: Comparison with magnetic resonance imaging and two-dimensional echocardiographic determinations in man
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DOI：
10.1023/a:1026540809758
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发表时间：
2000-10-01
期刊：
影响因子：
--
通讯作者：
Hibberd, MG
中科院分区：
文献类型：
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作者：
Chuang, ML;Beaudin, RA;Hibberd, MG
本研究旨在比较新型三维超声心动图（3DE）系统与临床二维超声心动图（2DE）和磁共振成像（MRI）测定人类左心室质量（LVM）的效果。左心室质量是心脏病发病率和死亡率的独立预测因子。超声心动图是评估左心室质量最广泛使用的临床方法，因为它是无创的，便携式的，相对便宜。然而，当测量左心室质量时，2DE受到心室形状假设的限制，而心室形状假设不影响3D回波。方法：对25例脑梗死患者行3DE、2DE及MRI检查。三维回波使用磁扫描头跟踪器，允许不受限制地选择和组合来自多个声学窗口的图像。使用7种不同的几何公式通过定量2DE评估质量。结果：MRI检查的左心室质量范围为91 ~ 316 g。3DE与MRI之间具有良好的一致性（r = 0.99，SEE = 6.9 g）。定量2D方法与MRI（r = 0.84-0.92）相关性良好，但低估了SEE的三倍（22.5-30.8 g）。3DE的观察者间差异为7.6%，2DE为17.7%。结论：相对于MRI，使用磁跟踪的经胸3D回波可以准确测量人体的左心室质量。与2D回波相比，3D超声心动图显著提高了准确性和可重复性。
This study was performed to compare a novel three-dimensional echocardiography (3DE) system to clinical two-dimensional echocardiography (2DE) and magnetic resonance imaging (MRI) for determination of left ventricular mass (LVM) in humans. LVM is an independent predictor of cardiac morbidity and mortality. Echocardiography is the most widely used clinical method for assessment of LVM, as it is non-invasive, portable and relatively inexpensive. However, when measuring LVM, 2DE is limited by assumptions about ventricular shape which do not affect 3D echo. Methods: A total of 25 unselected patients underwent 3DE, 2DE and MRI. Three-dimensional echo used a magnetic scanhead tracker allowing unrestricted selection and combination of images from multiple acoustic windows. Mass by quantitative 2DE was assessed using seven different geometric formulas. Results: LVM by MRI ranged from 91 to 316 g. There was excellent agreement between 3DE and MRI (r = 0.99, SEE = 6.9 g). Quantitative 2D methods correlated well with but underestimated MRI (r = 0.84-0.92) with SEEs over threefold greater (22.5-30.8 g). Interobserver variation was 7.6% for 3DE vs. 17.7% for 2DE. Conclusions: LVM in humans can be measured accurately, relative to MRI, by transthoracic 3D echo using magnetic tracking. Compared to 2D echo, 3D echocardiography significantly improves accuracy and reproducibility.