Clinical outcome in patients with high-grade internal carotid artery stenosis after irradiation

Clinical outcome in patients with high-grade internal carotid artery stenosis after irradiation
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DOI:
10.1212/01.wnl.0000176033.64896.c6
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发表时间:
2005-09-27
期刊:
影响因子:
9.9
通讯作者:
Henon, H
Henon, H
中科院分区:
医学1区
文献类型:
--
作者:
Marcel, M;Leys, D;Henon, H

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作者随访了41例颈内动脉狭窄≥ 70%且既往颈部放疗的患者(21例有症状)。28个月后,15例患者(36.6%)死亡,5例(12.2%)发生缺血性卒中,15例(36.6%)发生新的恶性肿瘤。新发恶性肿瘤是死亡的唯一独立预测因素。伊卡狭窄≥ 70%且既往颈部放疗患者的主要风险是恶性肿瘤,而不是卒中。
The authors followed up 41 consecutive patients (21 symptomatic) with internal carotid artery stenosis >= 70% and previous neck irradiation. After 28 months, 15 patients (36.6%) had died, five (12.2%) had had an ischemic stroke, and 15 (36.6%) had a new malignancy. Having a new malignancy was the only independent predictor of death. The major risk for patients with ICA stenosis >= 70% and previous neck irradiation is malignancy, not stroke.