Modulation of extrinsic and intrinsic processing by naturalistic audiovisual stimulation
Modulation of extrinsic and intrinsic processing by naturalistic audiovisual stimulation
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DOI：
10.32470/ccn.2019.1189-0
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Dror Cohen;Shinji Nishimoto
中科院分区：
文献类型：
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作者：
Dror Cohen;Shinji Nishimoto
大脑活动反映了外部刺激的处理（外部处理）和内部产生的信号的处理（内部处理）。内在加工与默认模式区域相关，而外在加工与感觉区域相关。然而，不同的刺激涉及不同的过程，使得外在处理的水平和程度随时间而变化。这些外在处理中的波动与内在处理中的波动之间的关系在很大程度上尚不清楚。在这里，我们提出了初步的结果（N = 2）调查如何外在（刺激反应）和内在（默认模式网络连接）处理自然视听刺激调制。我们把我们的分析集中在大脑区域（功能磁共振成像体素），显示了外在和内在的处理，我们确定整个皮层的混合物。聚类分析表明，在后脑区域的外在和内在的处理竞争，而在顶叶和额叶区域，他们可能合作。
Brain activity reflects both the processing of external stimuli (extrinsic processing) and the processing of signals generated internally (intrinsic processing). Intrinsic processing is associated with default mode areas whereas extrinsic processing is associated with sensory areas. However, different stimuli involve different processes such that the level and extent of extrinsic processing varies over time. The relationship between these fluctuations in extrinsic processing and fluctuations in intrinsic processing is largely unknown. Here we present preliminary results (N=2) investigating how extrinsic (stimulus-responses) and intrinsic (default mode network connectivity) processing are modulated by naturalistic audiovisual stimulation. We focus our analysis on brain areas (fMRI voxels) showing a mixture of extrinsic and intrinsic processing, which we identify throughout the cortex. Clustering analysis suggests that in posterior brain areas extrinsic and intrinsic processing compete, whereas in parietal and frontal areas they may cooperate.