Unemployment and work disability in individuals with chronic fatigue syndrome/myalgic encephalomyelitis: a community-based cross-sectional study from Spain
Unemployment and work disability in individuals with chronic fatigue syndrome/myalgic encephalomyelitis: a community-based cross-sectional study from Spain
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DOI：
10.1186/s12889-019-7225-z
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发表时间：
2019-06-28
影响因子：
4.5
通讯作者：
Alegre, Jose
中科院分区：
文献类型：
--
作者：
Castro-Marrero, Jesus;Faro, Monica;Alegre, Jose
背景：很少有报道研究慢性疲劳综合征/肌痛性脑脊髓炎（CFS/ME）患者的失业与工作残疾之间的关系。本研究探讨了CFS/ME队列中工作残疾的关键决定因素。方法：基于社区的前瞻性研究纳入1086例年龄在18-65岁的CFS/ME患者。记录人口统计学和临床特征以及结果测量。通过多元线性回归分析，确定工作残疾的主要风险指标。结果：有工作的CFS/ME患者450例（41.4%），失业的636例（58.6%）。发病年龄较大(OR: 1.44; 95% CI: 1；12-1.84，自主神经功能障碍（OR: 2.21; 95% CI: 1.71-2.87），神经症状(OR: 1.66; 95% CI: 1。在疲劳（OR: 2.61; 95% CI: 2.01-3.39）、疼痛（OR: 2.09; 95% CI: 1.47-2.97）、抑郁（OR: 1.98; 95% CI: 1）方面得分更高。20-3.26)、精神病理（OR: 1.98; 95% CI: 1.51-2.61）和睡眠障碍（OR: 1.47; 95% CI: 1）。14-1.90)都与较高的因病致残风险相关。结论：使用解释性方法，我们的研究结果表明，失业一直与CFS/ME导致的工作残疾风险增加有关，尽管现在需要进一步更严格的研究来帮助在工作场所进行针对性的干预。
Background: Few reports have examined the association between unemployment and work disability in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). This study explored the key determinants of work disability in a CFS/ME cohort.Methods: A community-based prospective study included 1086 CFS/ME patients aged 18-65 years. Demographic and clinical characteristics and outcome measures were recorded. Multiple linear regression analysis was performed to identify key risk indicators of work disability.Results: Four hundred and fifty patients with CFS/ME were employed (41.4%) and 636 were unemployed (58.6%). Older age at pain onset (OR: 1.44; 95% CI: 1. 12-1.84, autonomic dysfunction (OR: 2.21; 95% CI: 1.71-2.87), neurological symptom (OR: 1.66; 95% CI: 1. 30-2.13) and higher scores for fatigue (OR: 2.61; 95% CI: 2.01-3.39), pain (OR: 2.09; 95% CI: 1.47-2.97), depression (OR: 1.98; 95% CI: 1. 20-3.26), psychopathology (OR: 1.98; 95% CI: 1.51-2.61) and sleep dysfunction (OR: 1.47; 95% CI: 1. 14-1.90) were all associated with a higher risk of work disability due to illness.Conclusions: Using an explanatory approach, our findings suggest that unemployment is consistently associated with an increased risk of work disability due to CFS/ME, although further more rigorous research is now needed to help in targeting interventions at the workplace.