Persistent Organochlorine Pesticide Exposure Related to a Formerly Used Defense Site on St. Lawrence Island, Alaska: Data from Sentinel Fish and Human Sera.
Persistent Organochlorine Pesticide Exposure Related to a Formerly Used Defense Site on St. Lawrence Island, Alaska: Data from Sentinel Fish and Human Sera.
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DOI：
10.1080/15287394.2015.1037412
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Carpenter DO
中科院分区：
文献类型：
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作者：
Byrne S;Miller P;Waghiyi V;Buck CL;von Hippel FA;Carpenter DO
阿拉斯加州圣劳伦斯岛是白令海中最大的岛屿，距离西伯利亚60公里。该岛是大约1600名圣劳伦斯岛尤皮克居民的家园，他们过着勉强糊口的生活。该岛上存在两个以前使用过的防御工地(FUD)，其中之一，东北角，一直是1.23亿美元清理工作的对象。环境监测表明，土壤和流域受到多氯联苯(PCbs)、有机氯(OC)杀虫剂和砷的局部污染。这项研究调查了东北角FUDS是否是接触有机碳杀虫剂的来源。在现场修复期间，总共从代表该岛三个地理区域的志愿者那里收集了71份血清样本。此外，在修复后从东北开普省采集了九条刺鱼(Pungitius Pugitius)和阿拉斯加黑鱼(Dallia Ectoralis)，以评估有机碳杀虫剂的持续存在。氯丹化合物、滴滴涕化合物、灭蚁灵和六氯苯(HCB)是最普遍的化合物，在鱼类组织和人血清样本中的浓度最高。在控制了年龄和性别后，与距离现场最远的村庄的居民相比，东北角FUDS附近的活动与血清HCB的增加有关。氯丹和滴滴涕之间也存在正相关关系，但相关性不显著。鱼样本中的有机氯浓度没有显示出明显的地理趋势，但与阿拉斯加的其他地点相比似乎更高。综上所述，这些结果表明，东北角FUDS当地环境的污染可能会增加选择持久性有机化合物杀虫剂的暴露。
St. Lawrence Island, Alaska is the largest island in the Bering Sea, located 60 km from Siberia. The island is home to approximately 1600 St. Lawrence Island Yupik residents who live a subsistence lifestyle. Two formerly used defense sites (FUDS) exist on the island, one of which, Northeast Cape, has been the subject of a $123 million cleanup effort. Environmental monitoring demonstrates localized soil and watershed contamination with polychlorinated biphenyls (PCBs), organochlorine (OC) pesticides and arsenic. This study examined whether the Northeast Cape FUDS is a source of exposure to OC pesticides. A total of 71 serum samples were collected during site remediation from volunteers that represented three geographic regions of the island. Additionally, ninespine stickleback (Pungitius pungitius) and Alaska blackfish (Dallia pectoralis) were collected from Northeast Cape after remediation to assess continuing presence of OC pesticides. Chlordane compounds, DDT compounds, mirex and hexachlorobenzene (HCB) were the most prevalent and present at the highest concentrations in both fish tissues and human serum samples. After controlling for age and sex, activities near the Northeast Cape FUDS were associated with an increase in serum HCB as compared to residents of the farthest village from the site. Positive but non-significant relationships for sum-chlordane and sum-DDT were also found. Organochlorine concentrations in fish samples did not show clear geographic trends, but appear elevated compared to other sites in Alaska. Taken together, the results suggest that contamination of the local environment at the Northeast Cape FUDS may increase exposure to select persistent OC pesticides.