Differential processing of objects under various viewing conditions in the human lateral occipital complex
Differential processing of objects under various viewing conditions in the human lateral occipital complex
复制标题
DOI：
10.1016/s0896-6273(00)80832-6
复制
发表时间：
1999-09-01
期刊：
影响因子：
16.2
通讯作者：
Malach, R
中科院分区：
文献类型：
--
作者：
Grill-Spector, K;Kushnir, T;Malach, R
由于有限的空间分辨率，人类皮层神经元的不变性不能直接用fMRI研究。在这里，我们通过使用fMR自适应来规避这一限制，即由于重复呈现相同图像而减少fMR信号。对象选择性区域（外侧枕叶复合体[100]）显示出随着重复频率的增加单调信号减少。通过在不同的观看条件下呈现同一物体，研究了fMR自适应的不变性。与照明和视角相比，FMR对尺寸和位置的变化表现出更强的fMR适应性（更不变性）。该效应揭示了两个假定的细分内的尾-背（LO），表现出实质性的恢复适应下的所有转换，和后梭形（PF/LOa），表现出更强的适应。这项研究表明，实用程序的fMR适应揭示功能特性的神经元的fMRI研究。
The invariant properties of human cortical neurons cannot be studied directly by fMRI due to its limited spatial resolution. Here, we circumvented this limitation by using fMR adaptation, namely, reduction of the fMR signal due to repeated presentation of identical images. Object-selective regions (lateral occipital complex [LOC]) showed a monotonic signal decrease as repetition frequency increased. The invariant properties of fMR adaptation were studied by presenting the same object in different viewing conditions. LOC exhibited stronger fMR adaptation to changes in size and position (more invariance) compared to illumination and viewpoint. The effect revealed two putative subdivisions within LOG: caudal-dorsal (LO), which exhibited substantial recovery from adaptation under all transformations, and posterior fusiform (PF/LOa), which displayed stronger adaptation. This study demonstrates the utility of fMR adaptation for revealing functional characteristics of neurons in fMRI studies.