Genetics of subthalamic nucleus in development and disease.
Genetics of subthalamic nucleus in development and disease.
复制标题
发育和疾病中丘脑底核的遗传学。
DOI：
10.1016/j.expneurol.2004.11.008
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Martin,DonnaM
中科院分区：
文献类型：
--
作者：
Philips,StevenT;Albin,RogerL;Martin,DonnaM
The subthalamic nucleus (STN) is a crucial node in the basal ganglia. Clinical success in targeting the STN for deep brain stimulation in Parkinson's disease patients has prompted increased interest in understanding STN biology. In this report, we discuss recent evidence for transcription factor mediated regulation of STN development. We also review STN developmental neurobiology and known patterns of gene expression in the developing and mature STN.
