The Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2): design and methods
The Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2): design and methods
复制标题
DOI：
10.1002/mpr.317
复制
发表时间：
2010-09-01
影响因子：
3.1
通讯作者：
van Dorsselaer, Saskia
中科院分区：
文献类型：
--
作者：
de Graaf, Ron;Ten Have, Margreet;van Dorsselaer, Saskia
精神病学人口研究NEMESIS-2（荷兰精神健康调查和发病率研究-2）重复并扩展了1996年至1999年进行的第一次荷兰精神健康调查和发病率研究（NEMESIS-1）。这项新研究的主要目标是提供关于精神障碍的流行率、发病率、病程和后果的最新数字，并通过使用新的样本研究精神障碍和服务使用的趋势。加入了NEMESIS-1中未包含的新主题，例如冲动控制障碍，以及通过收集唾液样本中的DNA来确定精神障碍的遗传相关性。本文概述了NEMESIS-2的设计，特别是其最近完成的第一波。NEMESIS-2是一项前瞻性研究，研究对象为荷兰人，年龄在18-64岁之间。其基线波包括6646名受试者。计划进行三波，每波之间间隔三年。采用多阶段分层随机抽样方法。NEMESIS-2的基线波于2007年11月至2009年7月进行。采用复合国际诊断访谈（CIDI） 3.0进行面对面访谈。应答率为65.1%，76.4%的应答者捐献唾液。样本在全国范围内具有一定的代表性，但年轻受试者的代表性不足。总之，我们能够建立一个高质量的综合数据集，允许将来研究几个主题。版权所有John Wiley & Sons， Ltd。
The psychiatric epidemiological population study NEMESIS-2 (Netherlands Mental Health Survey and Incidence Study-2) replicates and expands the first Netherlands Mental Health Survey and Incidence Study (NEMESIS-1) conducted from 1996 to 1999. The main objectives of the new study are to provide up-to-date figures on the prevalence, incidence, course and consequences of mental disorders, and to study trends in mental disorders and service use, with the use of a new sample. New topics not included in NEMESIS-1 were added, e. g. impulse-control disorders, and genetic correlates of mental disorders through gathering DNA from saliva samples. This paper gives an overview of the design of NEMESIS-2, especially of its recently completed first wave. NEMESIS-2 is a prospective study among Dutch-speaking subjects aged 18-64 years from the general Dutch population. Its baseline wave included 6646 subjects. Three waves are planned with three year-intervals between the waves. A multistage, stratified random sampling procedure was applied. The baseline wave of NEMESIS-2 was performed between November 2007 and July 2009. Face-to-face interviews were administered with the Composite International Diagnostic Interview (CIDI) 3.0. The response rate was 65.1%, and 76.4% of the respondents donated saliva. The sample was reasonably nationally representative, but younger subjects were somewhat underrepresented. In conclusion, we were able to build a comprehensive dataset of good quality, permitting several topics to be studied in the future. Copyright (C) 2010 John Wiley & Sons, Ltd.