Seasonal modifications in blood pressure are mainly related to interdialytic body weight gain in dialysis patients
Seasonal modifications in blood pressure are mainly related to interdialytic body weight gain in dialysis patients
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DOI：
10.1111/j.1523-1755.2004.00569.x
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发表时间：
2004-05-01
影响因子：
19.6
通讯作者：
Mourad, G
中科院分区：
文献类型：
--
作者：
Argilés, A;Lorho, R;Mourad, G
背景资料。对透析患者的纵向研究发现，血压的季节性变化可能会遵循外部温度和湿度等气候参数。我们的目的是评估透析间期体重增加的变化在血压季节性变化中的作用。对1991年1月7日至1998年9月30日在单一卫星透析机进行透析的99例稳定患者(40例女性/59例男性)进行了研究，年龄为52.9+/-1.5岁。测定3069例透析者的仰卧位收缩压、舒张压、体重和透析间期体重增加。并与从法国Meteo获得的气候学数据一起进行了研究。血压在一年中变化不同，遵循周期性模式。从秋季到冬季，气温呈上升趋势，而在春季和偏暖月份，气温呈下降趋势。收缩压和舒张压与透析间期体重增加密切相关(r=0.925；P<；0.0001和r=0.888；P=0.0001)。降雨量(r=0.786；P<；0.003和r=0.784：P<；0.003)、湿度(r=0.701；P=0.011和r=0.699：P<；0.012)和日照时数(r=-0.658：P<；0.012)也与血压相关。以血压为因变量的多元回归分析保留了透析间期体重增长作为模型中的第一变量。我们的结果建立了血压变化和透析间期体重增加之间的强烈联系，表明容量状态在调节这类患者的血压中发挥了重要作用。
Background. Longitudinal studies in dialysis patients have identified seasonal variations in blood pressure that may follow climatic parameters such as external temperature and humidity. We aimed to assess the participation of interdialytic body weight gain variations in the seasonal profile of blood pressure.Methods. Ninety-nine stable patients (40 F/59 M), 52.9 +/- 1.5 years old, dialyzed in a single satellite dialysis unit between January 7, 1991, and September 30, 1998 were studied. Supine systolic and diastolic blood pressure, body weight, and interdialytic body weight gain were determined at every one of the 3069 dialyses included. and studied along with climatology data obtained from Meteo, France.Results. Blood pressure varied throughout the year, following a cyclic pattern. It increased from the autumn months toward winter, and decreased toward the spring and warmer months. Systolic and diastolic blood pressures were strongly correlated with interdialytic body weight gain (r = 0.925; P < 0.0001 and r = 0.888; P = 0.0001, respectively). Blood pressure was also correlated with the climatic factors: rainfall (r = 0.786;P < 0.003 and r = 0.784: P < 0.003), humidity (r = 0.701; P = 0.011 and r = 0.699: P < 0.012), and day light span (r = -0712; P < 0.01, and r = -0.658: P < 0.02, respectively). Multivariate regression analyses taking blood pressure as a dependent variable retained interdialytic body weight gain as the first variable in the model.Conclusion. Our results establish a strong link between blood pressure variations and interdialytic body weight gain, showing the important participation of volume state in modulating blood pressure in this group of patients.