International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: Transient receptor potential channels
International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: Transient receptor potential channels
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DOI：
10.1124/pr.55.4.6
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发表时间：
2003-12-01
影响因子：
21.1
通讯作者：
Julius, D
中科院分区：
文献类型：
--
作者：
Clapham, DE;Montell, C;Julius, D
瞬时受体电位（TRP）蛋白是六个跨膜亚基，它们联合收割机形成阳离子选择性离子通道。TRP通道存在于酵母、果蝇、秀丽隐杆线虫和哺乳动物中。它们广泛分布，并感知从光到温度和渗透压的刺激的局部变化。哺乳动物含有至少22个不同的基因编码这些离子通道。这篇摘要文章概述了TRP通道之间的分子关系及其标准命名法，该命名法源自IUPHAR电压门控离子通道纲要。(1)完整的纲要，包括TRP通道系列每个成员的数据表，可以在。
The transient receptor potential (TRP) proteins are six transmembrane-containing subunits that combine to form cation-selective ion channels. TRP channels are present in yeast, Drosophila, Caenorhabditis elegans, and mammals. They are widely distributed and sense local changes in stimuli ranging from light to temperature and osmolarity. Mammals contain at least 22 distinct genes encoding these ion channels. This summary article presents an overview of the molecular relationships among the TRP channels and a standard nomenclature for them, which is derived from the IUPHAR Compendium of Voltage-Gated Ion Channels.(1) The complete Compendium, including data tables for each member of the TRP channel family, can be found at .