Squamous cell carcinoma and precursor lesions of the oral cavity: epidemiology and aetiology
Squamous cell carcinoma and precursor lesions of the oral cavity: epidemiology and aetiology
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DOI：
10.1111/j.1600-0757.2011.00401.x
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发表时间：
2011-01-01
影响因子：
18.6
通讯作者：
Amarasinghe, A. A. Hemantha K.
中科院分区：
文献类型：
--
作者：
Johnson, Newell W.;Jayasekara, Prasanna;Amarasinghe, A. A. Hemantha K.
被诊断患有恶性肿瘤的人经常感到害怕和孤独。然而，癌症在很大程度上是一种可以避免的疾病，研究表明，超过三分之二的癌症死亡可以通过改变生活方式、早期发现和有效治疗来预防。世界卫生组织（WHO）估计，2008年全球发生了近1270万新发病例和760万癌症死亡病例（27）。口腔癌是影响口腔结构或组织的恶性肿瘤。它们可能是起源于口腔的原发性病变，来自远处部位的转移，或来自邻近部位的延伸。在引用详细的流行病学数据时，有必要区分这些起源，并确定包括哪些结构，例如嘴唇的朱红色边界有时包括，有时不包括。在全球范围内，口腔癌是癌症相关死亡的第八大常见原因，尽管许多人不知道它的存在（91）。在这些口腔癌中，超过90%是口腔和口咽粘膜中产生的鳞状细胞癌。
People diagnosed with malignant neoplasms often feel afraid and alone. However, cancer is largely an avoidable disease, and studies have shown that more than two-thirds of cancer deaths may be prevented through lifestyle modification, early detection and effective treatment. The World Health Organization (WHO) estimates that nearly 12.7 million new cases and 7.6 million cancer deaths occurred worldwide in 2008 (27).Oral cancers are malignant neoplasms that affect the structures or tissues of the mouth. They may be a primary lesion that originated in the mouth, a metastasis from a distant site, or an extension from an adjoining site. In quoting detailed epidemiological data, it is necessary to distinguish between these origins, and to ascertain which structures are included, eg the vermillion borders of the lips are sometimes included and sometimes not. Globally, Ôoral cancerÕ is the eighth most common cause of cancer-related deaths, although many people are unaware of its existence (91). Of these oral cancers, more than 90% are squamous cell carcinomas arising in the mucous membranes of the mouth and oropharynx.