The expression of human MAO-A and B genes.
The expression of human MAO-A and B genes.
复制标题
人类 MAO-A 和 B 基因的表达。
DOI：
10.1007/978-3-7091-9113-2_4
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Chen,K
中科院分区：
文献类型：
--
作者：
Shih,JC;Grimsby,J;Chen,K
用32P标记的人肝脏MAO-A和B亚片段进行Northern分析，在胎儿组织和成人脑中分别检测到5kb和3kb的转录本。测定了这些转录本的组织分布。除了MAO-A的5kb转录本外，小肠和胎盘还表达一个2kb的转录本，该转录本被确定为缺少3‘侧翼区域。MAO-A先于MAO-B在胎儿脑中出现，而MAO-A和MAO-B在成人脑中均有表达。
Northern analysis using32P-labeled subfragments of human liver MAO-A and B cDNA clones detected 5Kb and 3Kb transcripts, respectively in fetal tissues and adult brains. The tissue distribution of these transcripts was determined. Small intestine and placenta express, in addition to the MAO-A 5Kb transcript, a 2Kb transcript determined to lack a 3′ flanking region. MAO-A appeared prior to MAO-B in the fetal brain, whereas both MAO-A and B were found in adult brain.