Diet and the developing immune system
Diet and the developing immune system
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饮食和免疫系统的发育
作者：
S. Langley;L. J. Carrington
已知胎儿期营养不良对组织形态和功能具有编程效应。这通常会导致成年后健康状况不佳，在子宫内生长受限的个体中，代谢综合征和心血管死亡率的风险增加。生命早期的营养不良影响免疫器官的发育，似乎会降低细胞免疫力，增加儿童期特应性疾病的风险。有限的证据表明胎儿编程在自身免疫性疾病的发展。这一领域代表了进一步研究和预防医学的一个有趣的目标。
Undernutrition during fetal life is known to have programming effects upon tissue morphology and function. This generally promotes poor health in adult life, with increased risk of metabolic syndrome and cardiovascular mortality noted among individuals whose growth was constrained in utero. Undernutrition in early life impacts upon the development of the immune organs and appears to diminish cellular immunity and increase the risk of atopic disorders during childhood. A limited body of evidence implicates fetal programming in the development of autoimmune disorders. This area represents an interesting target for further research and preventive medicine.