FEMALE PROSTITUTES: A RISK GROUP FOR INFECTION WITH HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE III

FEMALE PROSTITUTES: A RISK GROUP FOR INFECTION WITH HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE III
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妓女:感染人类 T 细胞淋巴细胞病毒 III 型的高危人群

DOI:
10.1016/s0140-6736(85)90462-3
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发表时间:
1985
期刊:
The Lancet
影响因子:
--
通讯作者:
J. Kanyamupira
J. Kanyamupira
中科院分区:
--
文献类型:
--
作者:
P. Perre;M. Carael;M. Robert;N. Clumeck;E. Nzabihimana;P. Mol;P. Freyens;R. Gallo;J. Butzler;J. Kanyamupira

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1984年7月,对卢旺达的33名妓女和25名男妓进行了临床评估,并评估了她们的T淋巴细胞亚群和人类T细胞嗜淋巴病毒III型(HTLV-III)抗体频率。27名否认与妓女接触的健康男性,33名不是妓女的健康女性,以及1983年看到的51名卢旺达妓女作为对照。只有6名妓女无淋巴结炎(第一组),13名有原因不明的全身淋巴结病(淋巴结病)(第二组),14名有淋巴结炎和全身症状(第三组)。组II和组III的平均OKT 4/OKT 8比值显著低于组I或女性对照。在33名妓女中的29名、4名女性对照、7名男性顾客和2名男性对照中检测到HTLV-III抗体。在男性顾客中,HTLV-III血清阳性根据每年不同性伴侣的数量而增加。这项研究表明,在中非,妓女是HTLV-III感染的高危群体。
In July, 1984 33 female prostitutes in Rwanda and 25 male customers of prostitutes were assessed clinically and for their T-lymphocyte subsets and frequency of antibodies to human T-cell lymphotropic virus type III (HTLV-III). 27 healthy males who denied contact with prostitutes, 33 healthy women who were not prostitutes, and 51 Rwandese prostitutes seen in 1983 served as controls. Only 6 prostitutes were symptom-free (group I), 13 had unexplained generalised lymphadenopathy (LAP) (group II), and 14 had LAP and constitutional symptoms (group III). Mean OKT4/OKT8 ratio in groups II and III was significantly lower than that in group I or in female controls. HTLV-III antibodies were detected in 29 of 33 prostitutes, 4 female controls, 7 male customers, and 2 male controls. In male customers, HTLV-III seropositivity increased according to the number of different sexual partners per year. This study suggests that in Central Africa prostitutes are a high-risk group for HTLV-III infection.
人类 T 细胞白血病病毒 III 型明显传播给患有获得性免疫缺陷综合征的异性恋女性。
DOI: 10.7326/0003-4819-102-1-63
发表时间: 1985
影响因子: 39.2
作者:
Groopman,JE;Sarngadharan,MG;Salahuddin,SZ;Buxbaum,R;Huberman,MS;Kinniburgh,J;Sliski,A;McLane,MF;Essex,M;Gallo,RC
通讯作者: Gallo,RC