KSHV (HHV8) vaccine: promises and potential pitfalls for a new anti-cancer vaccine.
KSHV (HHV8) vaccine: promises and potential pitfalls for a new anti-cancer vaccine.
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DOI：
10.1038/s41541-022-00535-4
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发表时间：
2022-09-20
期刊：
影响因子：
9.2
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中科院分区：
文献类型：
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Seven viruses cause at least 15% of the total cancer burden. Viral cancers have been described as the “low-hanging fruit” that can be potentially prevented or treated by new vaccines that would alter the course of global human cancer. Kaposi sarcoma herpesvirus (KSHV or HHV8) is the sole cause of Kaposi sarcoma, which primarily afflicts resource-poor and socially marginalized populations. This review summarizes a recent NIH-sponsored workshop’s findings on the epidemiology and biology of KSHV as an overlooked but potentially vaccine-preventable infection. The unique epidemiology of this virus provides opportunities to prevent its cancers if an effective, inexpensive, and well-tolerated vaccine can be developed and delivered.
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影响因子：
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作者：
Barasa AK;Ye P;Phelps M;Arivudainambi GT;Tison T;Ogembo JG
通讯作者：
Ogembo JG
DOI：
10.3390/v6093472
发表时间：
2014-09-19
期刊：
Viruses
影响因子：
--
作者：
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通讯作者：
Tosato G
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Wood, Charles
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通讯作者：
Whitby, Denise
影响因子：
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作者：
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通讯作者：
Bray, Freddie