Detection of gliotoxin in experimental and human aspergillosis
Detection of gliotoxin in experimental and human aspergillosis
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DOI：
10.1128/iai.73.1.635-637.2005
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发表时间：
2005-01-01
影响因子：
3.1
通讯作者：
Prince, RA
中科院分区：
文献类型：
--
作者：
Lewis, RE;Wiederhold, NP;Prince, RA
在实验诱导的侵袭性曲霉病（IA）小鼠的肺（平均值为3，976 +/-1，662 ng/g组织）和血清（平均值为36.5 +/- 30.28 ng/ml）中测定了胶粘毒素，抗真菌治疗后胶粘毒素水平降低。也可以在有记录（证实或可能）IA的癌症患者的血清中检测到胶粘毒素。
Gliotoxin was measured in the lungs (mean, 3,976 +/- 1,662 ng/g of tissue) and sera (mean, 36.5 +/- 30.28 ng/ml) of mice with experimentally induced invasive aspergillosis (IA), and levels decreased with antifungal therapy. Gliotoxin could also be detected in the sera of cancer patients with documented (proven or probable) IA.