Interpersonal Psychotherapy for Mental Health Problems: A Comprehensive Meta-Analysis
Interpersonal Psychotherapy for Mental Health Problems: A Comprehensive Meta-Analysis
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DOI：
10.1176/appi.ajp.2015.15091141
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发表时间：
2016-07-01
影响因子：
17.7
通讯作者：
Cristea, Ioana A.
中科院分区：
文献类型：
--
作者：
Cuijpers, Pim;Donker, Tara;Cristea, Ioana A.
目的：人际心理疗法（IPT）已被开发用于治疗抑郁症，但已被用于其他几种精神障碍。一个全面的荟萃分析的所有随机试验检查的影响，IPT为所有的心理健康problems.Method：在PubMed，Psyclnfo，Embase，和科克伦进行了识别所有的试验检查IPT为任何心理健康problems.Results：90项研究，11,434名参与者被纳入。与对照组相比，急性期抑郁的IPT具有中度至重度效应（g=0.60; 95%CI =0.45-0.75）。与其他治疗（差异g=0.06）和药物治疗（g=-0.13）无显著差异。联合治疗比单用IPT更有效（g=0.24）。阈下抑郁症的IPT显著预防了重性抑郁症的发作，维持IPT显著减少复发。IPT对进食障碍有显着的效果，但在治疗的急性期，其效果可能略小于认知行为疗法（CBT）。在焦虑症中，与对照组相比，IPT的效果很大，没有证据表明IPT的效果不如CBT。在大多数研究中存在科克伦协作网定义的偏倚风险。有一点点迹象表明，偏见的存在影响outcome.Conclusions：IPT是有效的抑郁症的急性治疗，并可能有效地预防新的抑郁症，并在防止复发。IPT也可以有效治疗进食障碍和焦虑症，并在其他一些心理健康疾病中显示出有希望的效果。
Objective: Interpersonal psychotherapy (IPT) has been developed for the treatment of depression but has been examined for several other mental disorders. A comprehensive meta-analysis of all randomized trials examining the effects of IPT for all mental health problems was conducted.Method: Searches in PubMed, Psyclnfo, Embase, and Cochrane were conducted to identify all trials examining IPT for any mental health problem.Results: Ninety studies with 11,434 participants were included. IPT for acute-phase depression had moderate-to-large effects compared with control groups (g=0.60; 95% CI=0.45-0.75). No significant difference was found with other therapies (differential g=0.06) and pharmacotherapy (g=-0.13). Combined treatment was more effective than IPT alone (g=0.24). IPT in subthreshold depression significantly prevented the onset of major depression, and maintenance IPT significantly reduced relapse. IPT had significant effects on eating disorders, but the effects are probably slightly smaller than those of cognitive-behavioral therapy (CBT) in the acute phase of treatment. In anxiety disorders, IPT had large effects compared with control groups, and there is no evidence that IPT was less effective than CBT. There was risk of bias as defined by the Cochrane Collaboration in the majority of studies. There was tittle indication that the presence of bias influenced outcome.Conclusions: IPT is effective in the acute treatment of depression and may be effective in the prevention of new depressive disorders and in preventing relapse. IPT may also be effective in the treatment of eating disorders and anxiety disorders and has shown promising effects in some other mental health disorders.