Etiopathogenesis of kidney disease in minority populations and an updated special focus on treatment in diabetes and hypertension.
Etiopathogenesis of kidney disease in minority populations and an updated special focus on treatment in diabetes and hypertension.
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DOI：
10.1016/j.jnma.2022.05.004
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发表时间：
2022-06
影响因子：
3.3
通讯作者：
Nicholas, Susanne B.
中科院分区：
文献类型：
--
作者：
Umeukeje, Ebele M.;Washington, Jasmine T.;Nicholas, Susanne B.
关键词：
糖尿病和高血压是一般人群以及黑人和非裔美国人人群中慢性肾病（CKD）的最常见原因，与白色人群相比，黑人和非裔美国人人群的CKD和CKD进展率也较高。CKD的进展可导致肾衰竭，并且患有进展性肾病的患者具有过早死亡的高风险，特别是心血管疾病。CKD的早期检测筛查很重要，因为它有助于启动药物治疗，这些药物已被证明可以延缓糖尿病相关和非糖尿病相关CKD的进展，并降低肾脏和心血管疾病的死亡率。使用一些较新的里诺和心脏保护降糖药物（如钠葡萄糖协同转运蛋白-2抑制剂）的潜在不良反应可以通过详细的患者教育和医疗保健提供者的监测来有效避免。值得注意的是，生活方式的改变，包括定期运动，饮食和戒烟是糖尿病和高血压管理的第一线。当CKD发生时，由提供者使用综合策略进行共同管理可能会避免早期并发症，并促进适当的肾脏专科护理的早期转诊。
Diabetes and hypertension are the most common causes of chronic kidney disease (CKD) in the general population as well as in the Black and African American population, who also suffer from high rates of CKD and CKD progression compared to the White population. Progression of CKD can lead to kidney failure, and patients with progressive kidney disease have a high risk of premature mortality, particularly from cardiovascular disease. Screening for early detection of CKD is important as it facilitates the initiation of medications that have shown to delay the progression of diabetes-related as well as non-diabetes-related CKD, and reduce rates of death from both kidney and cardiovascular disease. The potential adverse effects from use of some of the newer reno- and cardio-protective glucose-lowering medications, such as the sodium glucose cotransporter-2 inhibitors may be effectively avoided with detailed patient education and monitoring by the healthcare provider. It is important to note that lifestyle modification including regular exercise, diet and smoking cessation are first-line in the management of diabetes and hypertension. When CKD occurs, co-management by providers using a comprehensive strategy may avert early complications and facilitate appropriate early referral for nephrology specialty care.
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影响因子：
2.2
作者：
Polonsky WH;Henry RR
通讯作者：
Henry RR
影响因子：
3.3
作者：
Nicholas, Susanne B.;Kalantar-Zadeh, Kamyar;Norris, Keith C.
通讯作者：
Norris, Keith C.
DOI：
10.2215/cjn.13111215
发表时间：
2016-08-01
影响因子：
9.8
作者：
Afkarian, Maryam;Katz, Ronit;Young, Bessie
通讯作者：
Young, Bessie
影响因子：
5.5
作者：
Levin, Adeera;Stevens, Paul E.
通讯作者：
Stevens, Paul E.
DOI：
10.1053/j.ajkd.2016.05.019
发表时间：
2016-12
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Rebholz CM;Crews DC;Grams ME;Steffen LM;Levey AS;Miller ER 3rd;Appel LJ;Coresh J
通讯作者：
Coresh J