Vagal and sympathetic nerve activities influenced by posterior cerebral circulation in rabbits.
Vagal and sympathetic nerve activities influenced by posterior cerebral circulation in rabbits.
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兔子大脑后循环影响迷走神经和交感神经活动。
DOI：
10.3109/00016489309130236
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
T. Matsunaga
中科院分区：
文献类型：
--
作者：
K. Yamamoto;T. Kubo;T. Matsunaga
用5 ′-二磷酸腺苷（ADP;血小板聚集剂）部分阻断家兔椎动脉血流，记录迷走神经和交感神经活动。当一个小剂量的ADP（0.2毫克/公斤）被管理到一侧椎动脉，交感神经（SN）活动增加，其幅度与血压（BP）的下降程度呈负相关。较大剂量（2 mg/kg）的ADP抑制注射侧的SN活性，而非注射侧的变化很小。迷走神经（VN）的活动表现出双相兴奋性反应的两侧，虽然在注射侧比非注射侧的变化更大。结果表明，自主神经活动的不对称性在SN比VN更明显。目前的研究表明，自主神经功能的不对称性可能是由于小脑和脑干血流的变化。
Vagal and sympathetic nervous activities in the rabbit were recorded while vertebral blood flow was partially blocked by the injection of adenosine 5'-diphosphate (ADP; platelet aggregator). When a small dose of ADP (0.2 mg/kg) was administered into a unilateral vertebral artery, sympathetic nerve (SN) activity increased, and its magnitude was inversely correlated with the extent of the decrease in blood pressure (BP). A larger dose (2 mg/kg) of ADP suppressed SN activity on the injected side, whereas the change was small on the non-injected side. Vagal nerve (VN) activity showed a monophasic excitatory response on both sides, although the change was larger on the injected than on the non-injected side. As a result, asymmetry in autonomic nerve activity was more distinct in SN than in VN. The present study demonstrated that asymmetry of autonomic nervous function can result from changes in blood flow in the cerebellum and brainstem.