Monitoring Cerebral Oxygenation in Neonates: An Update.
Monitoring Cerebral Oxygenation in Neonates: An Update.
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DOI：
10.3389/fped.2017.00046
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发表时间：
2017
影响因子：
2.6
通讯作者：
Lemmers PM
中科院分区：
文献类型：
--
作者：
Dix LM;van Bel F;Lemmers PM
大脑的氧合并不总是反映在全身动脉的氧合上。因此，用近红外光谱(NIRS)监测局部脑血氧饱和度(RScO2)在新生儿重症监护中具有一定的应用价值。RScO2代表对大脑的氧气供应，而脑组织氧摄取率，即rScO2与全身动脉血氧饱和度的比率，反映了大脑的氧气利用情况。氧的供应和利用之间的平衡提供了对新生儿脑(病理)生理学的洞察。这篇综述强调了在新生儿重症监护病房中使用近红外光谱监测脑氧合的潜力和局限性。
Cerebral oxygenation is not always reflected by systemic arterial oxygenation. Therefore, regional cerebral oxygen saturation (rScO2) monitoring with near-infrared spectroscopy (NIRS) is of added value in neonatal intensive care. rScO2 represents oxygen supply to the brain, while cerebral fractional tissue oxygen extraction, which is the ratio between rScO2 and systemic arterial oxygen saturation, reflects cerebral oxygen utilization. The balance between oxygen supply and utilization provides insight in neonatal cerebral (patho-)physiology. This review highlights the potential and limitations of cerebral oxygenation monitoring with NIRS in the neonatal intensive care unit.