Gastroesophageal reflux and obstructive sleep apnea.
Gastroesophageal reflux and obstructive sleep apnea.
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胃食管反流和阻塞性睡眠呼吸暂停。
DOI：
10.1093/sleep/12.5.475
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发表时间：
1989
期刊：
影响因子：
5.6
通讯作者：
C. Samelson
中科院分区：
文献类型：
--
作者：
C. Samelson
胃食管（GE）反流发生频繁，足以被认为是一个重要的睡眠相关功能障碍，其原因尚未得到充分阐明。注意力已被引导到至少两个组成部分，即食管下括约肌功能不全和第二不能快速清除反流物质。胃灼热、口腔酸味、下胸部和/或上腹部疼痛以及睡眠障碍的症状通常难以与其他睡眠相关疾病（如阻塞性睡眠呼吸暂停（OSA）、睡眠相关哮喘、阵发性夜间呼吸困难和异常吞咽综合征）区分，这些疾病可能与胃食管反流相关
Gastroesophageal (GE) reflux occurs frequently enough to be considered an important sleep-related dysfunction, the cause of which has not been sufficiently elucidated. Attention has been directed to at least two components, that of an incompetent lower esophageal sphincter and second an inability to clear refluxed material quickly. The symptoms of heartburn, acid taste in mouth, pain in lower chest and/or upper abdomen, and disturbance of sleep are often difficult to differentiate from other sleep-associated disorders such as obstructive sleep apnea (OSA), sleep-related asthma, paroxysmal nocturnal dyspnea, and abnormal swallowing syndrome with which GE reflux may be concomitantly associated