A quantitative index for the measurement of the tortuosity of blood vessels
A quantitative index for the measurement of the tortuosity of blood vessels
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DOI：
10.1016/s1350-4533(00)00074-6
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发表时间：
2000-10-01
影响因子：
2.2
通讯作者：
Varro, J
中科院分区：
文献类型：
--
作者：
Dougherty, G;Varro, J
我们提出了一种新的指标定量动脉扭曲，基于二次差异的坐标的血管中线。该指数与图像的放大倍数和采样频率无关。我们已经证明了它的有效性，作为形态学变化的一个指标，使用模拟的形状。它优于先前文献中提出的基于血管伸长和血管中线坐标差异方差的其他两种推定指标。所提出的指数很容易推广到三维，允许一个真正的三维扭曲指数计算从双平面血管摄影或连续断层扫描切片。它有许多临床应用。初步资料显示腹主动脉扭曲程度与受试者年龄有显著相关性(r=0.684， P
We propose a novel index for quantitating arterial tortuosity, based on second differences of the coordinates of the Vessel midline. The index is independent of the magnification of the image and of sampling frequency. We have demonstrated its validity as an indicator of changes in morphology using simulated shapes. It is superior to two other putative indices based on vessel elongation and the variance of differences in the vessel midline coordinates, presented previously in the literature. The proposed index is easily generalised to three dimensions, allowing a true three-dimensional tortuosity index to be calculated from biplane angiograms or serial tomographic slices. It has a number of clinical applications. Preliminary data, using 82 aortograms from radiographic archives, showed a significant correlation between the tortuosity of the abdominal aorta and subject age (r=0.684, P