Static indentation of anisotropic biomaterials using axially asymmetric indenters - A computational study
Static indentation of anisotropic biomaterials using axially asymmetric indenters - A computational study
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DOI：
10.1115/1.1785808
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发表时间：
2004-08-01
影响因子：
1.7
通讯作者：
Bischoff, JE
中科院分区：
文献类型：
--
作者：
Bischoff, JE
生物力学历史上一直使用压痕来提取生物组织的小应变弹性或粘弹性特性。然而，由于这些研究中使用的压头的轴对称性，结果分析需要假设材料各向同性，并且通常会产生“有效”弹性模量。由于已知大多数生物组织（例如骨骼和心肌）是各向异性的，因此用于估计材料特性的传统压痕技术的使用受到限制。这里使用有限元分析探讨了使用轴向不对称压头确定各向异性组织的材料方向和面内材料属性的可行性。通过压头测量的载荷与位移曲线取决于压头横截面相对于面内材料轴的方向，因此提出了一种用于确定下面材料方向的方法。此外，组织对压痕响应的刚度对面内各向异性材料特性和预拉伸的值敏感，因此测试结果可用于反演相关的本构参数。
Indentation has historically been used by biomechanicians to extract the small strain elastic or viscoelastic properties of biological tissues. Because of the axisymmetry of indenters used in these studies however analysis of the results requires the assumption of material isotropy and often yields an "effective" elastic modulus. Since most biological tissues such as bone and myocardium are known to be anisotropic, the use of conventional indentation techniques for estimating material properties is therefore limited. The feasibility of using an axially asymmetric indenter to determine material directions and inplane material properties for anisotropic tissue is explored here using finite element analysis. The load versus displacement curves as would be measured by an indenter depend on the orientation of the indenter cross section relative to the in-plane material axes, thus suggesting a method for determining the underlying material directions. Additionally, the stiffness of the tissue response to indentation is sensitive to the values of the in-plane anisotropic material properties and prestretches, and thus test results can be used to back out relevant constitutive parameters.