DISCHARGE PATTERNS OF BRAIN-STEM RESPIRATORY NEURONS IN RELATION TO CARBON DIOXIDE TENSION
DISCHARGE PATTERNS OF BRAIN-STEM RESPIRATORY NEURONS IN RELATION TO CARBON DIOXIDE TENSION
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DOI：
10.1152/jn.1968.31.2.142
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发表时间：
1968-01-01
影响因子：
2.5
通讯作者：
COHEN, MI
中科院分区：
文献类型：
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作者：
COHEN, MI
在患有气胸和神经肌肉阻滞的双侧迷走神经切断的猫中，研究了肺泡二氧化碳张力的变化对延髓和下部呼吸神经元放电模式的影响。膈神经放电可作为控制呼吸周期性的指标。对CO2水平降低的反应分为3种类型： 第1类：呼吸周期所有部分的放电频率减少，并且在足够低的CO2水平下放电消失；类型2：循环中某些部分放电频率增加而其他部分减少，并且在足够低的CO2水平下发生连续放电而没有呼吸调节；类型3：循环所有部分的放电频率减少，并且在足够低的CO2水平下发生连续放电而没有呼吸调节。不同类型的反应可能反映了各种呼吸神经元功能作用的差异。
In bilaterally vagotomized cats with pneumothorax and neuromuscular block, the effects of changes in alveolar CO2 tension on discharge patterns of medullary and potine respiratory neurons were studied; the phrenic nerve discharge served as indicator of contral respiratory periodicity. The responses to reduction of CO2 level were classified into 3 types: type 1: reduction of discharge frequency in all portions of the respiratory cycle, and disappearance of discharge at sufficiently low CO2 level; type 2: increase of discharge frequency in some portions and decrease in other portions of the cycle, and occurrence of continuous discharge without respiratory modulation at sufficiently low CO2 level; type 3: reduction of discharge frequency in all portions of the cycle, and occurrence of continuous discharge without respiratory modulation at sufficiently low CO2 level. The different types of response may reflect differences in the functional roles of various kinds of respiratory neuron.